Examples of 'compound libraries' in a sentence
Meaning of "compound libraries"
Compound libraries: A collection of diverse chemical compounds created for the purpose of drug discovery and development. These libraries contain a large number of compounds that researchers can screen to identify potential lead compounds for drug development
How to use "compound libraries" in a sentence
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compound libraries
Preferably compound libraries are screened in the methods herein.
Be identified by screening small compound libraries.
Synthetic compound libraries are commercially available.
These are components of compound libraries.
Many screening compound libraries often contain fluorescent compounds.
Lead compounds were identified and further compound libraries were obtained.
Such compound libraries are herein also referred to as candidate compound libraries.
They may be used for the screening of compound libraries.
It also provides the production of compound libraries through combinatorial chemistry of peptides.
The present invention provides methods to genetically encode compound libraries.
Compound libraries are prepared by multiple parallel synthesis using solution phase chemistry.
A means of handling the input from large compound libraries is needed.
The genetically encoded compound libraries are assayed by either screening or selection procedures.
High speed is absolutely crucial for screening large compound libraries.
Complementary pairs of compound libraries which include substrates or inhibitors of proteolytic enzymes.
See also
We have now determined that zone screening may be successfully applied to chemical compound libraries.
Methods for synthesising and screening compound libraries are known to those skilled in the art.
In particular, the compounds to screen are included in chemical compound libraries.
Screening of small molecule compound libraries with different protein targets requires sufficient amounts of compound.
The present invention comprises also genetically encoded combinatorial compound libraries generated with the methods described.
NRC has screened compound libraries of existing drugs to identify new inhibitors of protein glycation.
In some embodiments, the housing selectively binds members of compound libraries.
This is a historic challenge for macrocyclic compound libraries built in the biotechnology and pharmaceutical companies.
Compound libraries can comprise structurally related, structurally diverse, or structurally unrelated compounds.
In certain embodiments, the compound libraries are immobilized on a solid support.
Thus, a need exists for new methods and apparatus which permit the rapid screening compound libraries.
Similarly, compound libraries have been screened using affinity chromatography in combination with mass spectrometry.
In this regard, various methods for screening compound libraries have been reported.
Thus, screening of compound libraries begin immediately upon the preparation of the protein target.
This Chk1 kinase ELISA HTS allowed for the robotic screening of compound libraries.
Themed compound libraries ( BIOMOL ) were used for primary and secondary screening.
Peptide libraries, antibody libraries, or chemical compound libraries.
Is it worthwhile purchasing compound libraries or should one use the public NIH library?
The assay was scaled-down to a 384 well plate format for screening of chemical compound libraries.
A representative apparatus for screening compound libraries using a plurality of columns is illustrated in Figure 2.
In some embodiments, frontal affinity chromatography ( FAC ) can be used for screening of compound libraries.
Hits from these compound libraries are identified through the use of high throughput screening ( HTS ).
AstraZeneca and Sanofi today announced a direct exchange of 210,000 compounds from their respective proprietary compound libraries.
For example, synthetic compound libraries are commercially available from Maybridge Chemical Co.
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This compound will be evaluated in pulmonary hypertension
But it can only compound our problems
Examples of using Libraries
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The use of the libraries is free of charge
Libraries are independent in the formation of their collections
The relevance of reference libraries needs to be demonstrated
