Examples of 'conservative substitution' in a sentence
Meaning of "conservative substitution"
Conservative substitution: This phrase refers to a cautious or safe replacement or alternative. It is commonly used in the context of making a switch or trade-off that maintains a traditional or risk-averse approach
How to use "conservative substitution" in a sentence
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conservative substitution
The conservative mutation is typically a conservative substitution.
Conservative substitution tables are readily available in the art.
The representative conservative mutation is a conservative substitution.
A conservative substitution can be a first substitution.
The modification of amino acids is preferably conservative substitution.
Leucine is a conservative substitution for alanine.
A representative example of the conservative mutation is a conservative substitution.
There is no conservative substitution that will eliminate the potential epitope.
A typical conservative variation is conservative substitution.
Conservative substitution of amino acids are known to those skilled in the art.
The amino acid substitution is preferably conservative substitution.
The meaning of a conservative substitution is well known to the person skilled in the art.
It is to be understood that the claims encompass conservative substitution.
Such conservative substitution of amino acids is well known to those skilled in the art.
Preferably said substitution is a conservative substitution.
See also
A conservative substitution is the substitution of one amino acid for another with similar characteristics.
Amino acid substitution within each of these groups is called conservative substitution.
Amino acid sequences differing only by conservative substitution or minor length variations are substantially similar.
Alanine and valine are both aliphatic amino acids resulting in a conservative substitution.
Conservative substitution tables providing functionally similar natural amino acids are well known in the art.
The antibody of any of the preceding claims comprising a conservative substitution in the CDRs.
Especially, the conservative substitution is preferable.
In other embodiments the one or more amino acid is substituted with a conservative substitution.
In one embodiment, one conservative substitution is included in the peptide.
That is, the substitution is preferably a conservative substitution.
In certain embodiments, a conservative substitution includes a leucine to serine substitution.
In some embodiments, the substitution is a conservative substitution.
In one embodiment, one conservative substitution is included in the variant.
In one embodiment, the substitution is a conservative substitution.
The most conservative substitution is found under the heading of " preferred substitutions ".
The invention also provides a peptide which is a conservative substitution of the above peptide.
Preferably, the conservative substitution is a substitution selected from the group consisting of,.
In favorable circumstances, the substitution is a conservative substitution.
A substitution may be a conservative or a non-conservative substitution, preferably the substitution is a conservative substitution.
In preferred embodiments, one or more mutations is a conservative substitution.
Conservative substitution can also include substitution with a non-standard amino acid.
Particular protein modifications considered minor include conservative substitution of amino acids with similar chemical properties.
The differences are, preferably, differences or changes at a non essential residue or a conservative substitution.
Such a conservative substitution of amino acid ( s ) is well known to those skilled in the art.
Preferably, said substitutions are conservative substitution.
In any of these conservative substitution embodiments, any of the above-described compounds can be used.
And thus, such a substitution is defined as a conservative substitution.
In this regard, any conservative substitution variant of the above-described polypeptide sequences is contemplated herein.
Preferably, a substitution mutation is a conservative substitution.
Conservative substitution groups,.
For example, substitution of a phenylalanine for a tyrosine is a conservative substitution.
Substitutions may be introduced into conservative substitution sites or more preferably into non-conserved sites.
In terms of this point, particularly preferable one is a conservative substitution.
Still another alternative of conservative substitution is presented in Table 3 below,.
The nucleic acid molecule of claim 2, wherein said substitution is a conservative substitution.
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