Examples of 'cyclic nucleotide' in a sentence
Meaning of "cyclic nucleotide"
cyclic nucleotide - Cyclic nucleotides are a class of molecules that play important roles in intracellular signaling pathways. They are involved in mediating various physiological processes in cells by acting as secondary messengers. Examples include cAMP (cyclic adenosine monophosphate) and cGMP (cyclic guanosine monophosphate)
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- Any nucleotide in which the phosphate group is bonded to two hydroxyl groups on the same sugar
How to use "cyclic nucleotide" in a sentence
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cyclic nucleotide
Each cyclic nucleotide has three components.
The regulation occurs at the cyclic nucleotide hydrolysis phase.
Cyclic nucleotide phosphodiesterases are a family of phosphodiesterases.
Both prostaglandins had no effect on left atrial cyclic nucleotide content.
Cyclic nucleotide gated ion channel.
Control of lipogenesis by glucagon and cyclic nucleotide derivatives was examined in freshly isolated hepatocytes.
The invention is thus based on the identification of a novel human cyclic nucleotide phosphodiesterase.
The cyclic nucleotide phosphodiesterases are often abbreviated as phosphodiesterases.
In a preferred embodiment the eucaryotic cell lacks endogenous cyclic nucleotide phosphodiesterase activity.
The cyclic nucleotide.
Useful variations also include changes that provide for affinity for another cyclic nucleotide.
Journal of cyclic nucleotide research.
Analysis of the assembled sequence revealed that the cloned cDNA molecule encodes a cyclic nucleotide phosphodiesterase.
Defects in cyclic nucleotide phosphodiesterases have also been associated with retinal disease.
The cells in TCA were homogenized and sonicated to release cyclic nucleotide.
See also
A list of cyclic nucleotide phosphodiesterase inhibitors is given in Beavo supra.
Cilostazol was originally developed as a selective inhibitor of cyclic nucleotide phosphodiesterase 3.
The primary cyclic nucleotide operating in conjunction with the HCN channel is cAMP.
Subsequent to activation, the secretion of granules is under cyclic nucleotide regulation.
The cDNA sequence of a cyclic nucleotide dependent calcium channel Genbank No.
A cellular mechanism for the inactivation of cAMP is its breakdown by cyclic nucleotide phosphodiesterases ( PDEs ).
Cyclic nucleotide phosphodiesterases, molecular regulation to clinical use.
They regulate the localization, duration, and amplitude of cyclic nucleotide signaling within subcellular domains.
Cyclic nucleotide phosphodiesterases, functional implications of multiple isoforms.
Cilostazol has long been known as a cyclic nucleotide PDE3 inhibitor.
Accordingly, cyclic nucleotide phosphodiesterases are a major target for drug action and development.
The sequence includes HXXDHXX, a consensus amino acid sequence in cyclic nucleotide phosphodiesterases.
Cyclic nucleotide phosphodiesterases ( PDEs ) are a family of enzymes that catalyse the degradation of cyclic nucleotides.
PDE activity was expressed as pmol cyclic nucleotide hydrolyzed / min / ml of enzyme preparation.
By cyclic nucleotide assays, baicalin enhanced both cAMP and cGMP levels in mesenteric arteries.
Cyclic guanosine monophosphate ( cGMP ) is a cyclic nucleotide derived from guanosine triphosphate GTP.
Cyclic nucleotide phosphodiesterases ( PDEs ) have received considerable attention as molecular targets for anti-asthmatic agents.
XI % All four compounds tested for inhibition of cyclic nucleotide showed negligible absolute bioavailability.
Cyclic nucleotide phosphodiesterase 1C promotes human arterial smooth muscle cell proliferation.
The product was separated from the cyclic nucleotide substrate by chromatography on BioRad Affi-Gel 601.
A Type 7 cyclic nucleotide phosphodiesterase family member is found in high concentrations in skeletal muscle.
Figure 7 illustrates the effects of sulindac sulfide on cyclic nucleotide levels in HT-29 cells.
Elevation of levels of cyclic nucleotides can be accomplished by cyclic nucleotide phosphodiesterase ( PDE ) inhibition.
Beavo JA, Cyclic nucleotide phosphodiesterases, functional implications of multiple isoforms.
This cyclic nucleotide in turn activates protein kinase A ( PKA ; cAMP-dependent protein kinase ).
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A direct sum of finite cyclic groups is periodic
A cyclic system with a before and an after
Examples of using Nucleotide
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Sofosbuvir is a nucleotide prodrug that is extensively metabolised
Each pair is made up of something called a nucleotide
All of your nucleotide sequences are accounted for
