Examples of 'cyclooxygenase' in a sentence
Meaning of "cyclooxygenase"
Cyclooxygenase is a noun referring to an enzyme responsible for the formation of prostaglandins from arachidonic acid
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- Any of several enzymes that catalyze a cyclooxygenation reaction, but especially the conversion of arachidonic acid into prostaglandins (prostanoids); their inhibition is the mode of action of the NSAIDs aspirin and ibuprofen.
How to use "cyclooxygenase" in a sentence
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cyclooxygenase
Blocking the action of cyclooxygenase in the body.
The cyclooxygenase inhibitors can be exemplified by aspirin.
Aspirin blocks an enzyme called cyclooxygenase.
Cyclooxygenase is responsible for generation of prostaglandins.
Aspirin blocks the cyclooxygenase enzymes in all cells.
Cyclooxygenase is required for prostaglandin and thromboxane synthesis.
These agents inhibit cyclooxygenase dependent prostaglandin synthesis.
Cyclooxygenase is involved in numerous metabolic pathways.
They block the effect of an enzyme called cyclooxygenase.
The enzyme cyclooxygenase is responsible for generation of prostaglandins.
This release was blocked by fatty acid cyclooxygenase inhibitors.
Each type of cyclooxygenase lends itself to producing different types of prostaglandins.
These can be attributed to inhibition of cyclooxygenase p.
Ibuprofen protects platelet cyclooxygenase from irreversible inhibition by aspirin.
An important enzyme in this arachidonic acid metabolism is cyclooxygenase.
See also
The production of various cyclooxygenase products by the cultures was examined.
Ibuprofen is a reversible inhibitor of platelet cyclooxygenase.
A cyclooxygenase inhibitor was added to prevent generation of prostaglandins in the perfusion system.
It acts as a reversible cyclooxygenase inhibitor.
The preferred cyclooxygenase inhibitors were tested according to the above procedure.
This enzyme seems to work in part by breaking down cyclooxygenase.
Cyclooxygenase inhibitors will inhibit the formation of all three products.
The enzyme inhibitor may be a protease inhibitor or a cyclooxygenase inhibitor.
The inhibition of the platelet cyclooxygenase is the result of its acetylation by aspirin.
Indomethacin was used to inhibit prostaglandin synthesis through the cyclooxygenase pathway.
Cyclooxygenase and peroxidase levels in the absence of heme gave negative results.
Ibuprofen and other NSAIDs work by inhibiting a protein called cyclooxygenase.
The arachidonate is then acted upon by the cyclooxygenase component of prostaglandin synthase.
Previous NSAIDs have been found to inhibit some enzymes including cyclooxygenase.
Numerous methods can be used to determine the cyclooxygenase activity of a biological sample.
The present invention preferably includes compounds which selectively inhibit cyclooxygenase.
Preferred cyclooxygenase inhibitors for use in the present invention are keterolac and indomethacin.
Pregabalin does not block sodium channels or alter cyclooxygenase enzyme activity.
Cyclooxygenase is required to convert arachidonic acid to prostaglandins and other biologically active molecules.
The compounds of the invention are also arachidonic acid cyclooxygenase inhibitors.
The cyclooxygenase inhibitory activity of a drug can be determined by methods known in the art.
The results suggest a complex interaction between adrenergic and cyclooxygenase activation.
Cyclooxygenase inhibitors are associated with some adverse systemic side effects when applied conventionally.
It is an inhibitor of cyclooxygenase.
The compounds inhibit the cyclooxygenase pathway and may additionally inhibit the lipoxygenase pathway.
One example of this is the discovery of an inducible form of the cyclooxygenase enzyme.
This invention relates to methods of treating cyclooxygenase mediated diseases and certain pharmaceutical compositions therefor.
This species contains antioxidants and may partially inhibit the enzyme cyclooxygenase.
Potentiation of cyclooxygenase and peroxidase activities by aggregated AB peptides.
They are derived from fatty acids through oxygenation by cyclooxygenase and lipoxygenase enzymes.
The cyclooxygenase and lipoxygenase metabolites of EPA have attenuated activity.
Both antiinflammatory activity and analgesic activity are associated inhibition of the action of cyclooxygenase.
NSAIDs inhibit the metabolism by cyclooxygenase of arachidonic acid released by phospholipases.
This invention relates to compound and pharmaceutical compositions for the treatment of cyclooxygenase mediated diseases.
NSAIDs block the activity of cyclooxygenase enzymes thereby preventing eicosanoid formation.
