Examples of 'dalbavancin' in a sentence
Meaning of "dalbavancin"
Dalbavancin is a noun referring to an antibiotic used to treat skin infections, specifically in the class of lipoglycopeptide antibiotics
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- A lipoglycopeptide antibiotic.
How to use "dalbavancin" in a sentence
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dalbavancin
It is unknown whether dalbavancin is excreted in human milk.
Dalbavancin is typically administered to an individual as a dalbavancin composition.
Methicillin resistance has no impact on dalbavancin activity.
Dalbavancin is generally administered in a pharmaceutically acceptable carrier.
It is not known if dalbavancin is an inhibitor of transporters.
Dalbavancin may be administered as a single dose or as multiple doses.
Methods of administering dalbavancin for treatment of bacterial infections.
It contains the active substance dalbavancin.
Dalbavancin is a lipoglycopeptide belonging in the same glycopeptide class as vancomycin.
There are no data from the use of dalbavancin in pregnant women.
Dalbavancin compositions may be administered in a single dose or in multiple doses.
The active substance is dalbavancin.
Potential for dalbavancin to affect the pharmacokinetics of other medicinal products.
These results help to explain some of the unique pharmacokinetic characteristics of dalbavancin.
There is no experience with dalbavancin in the treatment of severely immunocompromised patients.
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Figure 3 depicts an electrospray ionization mass spectrum of dalbavancin.
Dalbavancin is a bactericidal lipoglycopeptide.
Information on the efficacy and safety of dalbavancin in patients with creatinine clearance.
Dalbavancin toxicity has been evaluated after daily intravenous administration for durations of up to.
A minimum bactericidal concentration of dalbavancin in plasma is typically about 4 mg / l.
Dalbavancin is also characterized by a marked bactericidal character and a synergism with penicillin.
This supports the use of dalbavancin as a once-weekly regimen.
Dalbavancin plasma concentrations were determined using validated liquid chromatography and mass spectrophotometer methods.
If an allergic reaction occurs, treatment with dalbavancin should be discontinued.
No reduction in dalbavancin concentration with respect to time zero samples was observed.
There is currently no data on cross-reactivity between dalbavancin and vancomyin.
It is not known if dalbavancin is a substrate for hepatic uptake and efflux transporters.
As mentioned, it is believed that ionic interactions are important in dalbavancin multimer stability.
The amount of dalbavancin administered may be any of the dosages disclosed herein.
In other words, each protein apparently binds two dalbavancin molecules.
Treatment of overdose with dalbavancin should consist of observation and general supportive measures.
Co-administration with inhibitors of these transporters may increase the exposure to dalbavancin.
Dalbavancin has been shown to work against bacteria such as methicillin resistant Staphylococcus aureus MRSA.
Clinical drug-drug interaction studies with dalbavancin have not been conducted.
Dalbavancin was well-tolerated in this study.
In yet another specific embodiment of interest, the glycopeptide antibacterial agent is dalbavancin.
Resistance to dalbavancin in Staphylococcus spp.
All Gram-negative bacteria are inherently resistant to dalbavancin.
Dalbavancin is reversibly bound to human plasma proteins, primarily to albumin.
When multiple doses are employed, dalbavancin can be administered weekly for two or more weeks.
Dalbavancin concentration in processed samples was stable after 24 hours at room temperature.
An example of a method for quantitating dalbavancin in plasma is provided in Example 5.
Binding of dalbavancin to a-glycoprotein is much greater than that of teicoplanin.
For isolates that persisted, there was no change in dalbavancin MIC.
Dalbavancin is often provided as a hydrochloride salt, which is freely soluble in water.
HSA increased the solubility of dalbavancin and reduced its binding affinity for the tri-peptide ligand.
Dalbavancin has better activity against streptococci, including penicillin-resistant strains, than teicoplanin or vancomycin.
After reconstitution each ml contains 20 mg dalbavancin.
Detectable dalbavancin concentration was stable after three cycles of freeze-thaw treatment.
The reconstituted concentrate in the vial contains 20 mg / ml dalbavancin.
