Examples of 'daratumumab' in a sentence
Meaning of "daratumumab"
Daratumumab: A monoclonal antibody used in the treatment of multiple myeloma
Show more definitions
- An antineoplastic.
How to use "daratumumab" in a sentence
Basic
Advanced
daratumumab
Darzalex contains the active substance daratumumab.
The efficacy of daratumumab was demonstrated in two clinical trials.
There is no known specific antidote for daratumumab overdose.
Daratumumab works by recognizing and attaching to these cancer cells.
I think there is very interesting studies going on with daratumumab.
Daratumumab is also being studied in the treatment of other types of cancer.
The active substance is daratumumab.
No formal studies of daratumumab in patients with hepatic impairment have been conducted.
Patients should be typed and screened prior to starting daratumumab treatment.
No formal studies of daratumumab in patients with renal impairment have been conducted.
No animal studies have been performed to establish the carcinogenic potential of daratumumab.
It is not known whether daratumumab is excreted into human or animal milk.
Daratumumab as a large protein has a low likelihood of direct ion channel interactions.
Some patients receiving daratumumab may experience cough and nasal congestion.
Daratumumab is the first monoclonal antibody approved for newly diagnosed patients with multiple myeloma.
See also
Phenotyping may be considered prior to starting daratumumab treatment as per local practice.
I am currently in a clinical trial for SMM patients using daratumumab.
All patients who received at least one dose of daratumumab were included in the analysis.
DARZALEX is a cancer medicine that contains the active substance daratumumab.
Your doctor may decrease your dose of daratumumab or temporarily or permanently stop your treatment.
NK cells in peripheral whole blood and bone marrow were observed with daratumumab treatment.
The effect of daratumumab on newborns / infants is unknown.
A higher incidence of neutropenia and pneumonia was observed in the daratumumab group . ”.
Then patients received daratumumab every 4 weeks until disease progression occurred.
As such, variations in drug-metabolising enzymes are not expected to affect the elimination of daratumumab.
Daratumumab concentration-time profiles were similar following the monotherapy and combination therapies.
This study adds to the growing body of evidence for daratumumab in the frontline setting . ”.
Following the start of daratumumab treatment, none of the patients tested positive for anti-daratumumab antibodies.
One mL of concentrate contains 20 mg daratumumab.
Daratumumab induced apoptosis in vitro after Fc mediated cross-linking.
In this study, the efficacy of daratumumab was evaluated in a patient-derived DLBCL model.
Daratumumab is a monoclonal antibody that exhibits high affinity for the CD38 receptor.
DARZALEX 20 mg / mL concentrate for solution for infusion daratumumab.
Janssen 's daratumumab accepted for accelerated CHMP assessment.
An exemplary anti-CD38 antibody that may be used is daratumumab.
Daratumumab was administered at 10 mg / kg once a week for four weeks.
Patients received either daratumumab plus Rd or Rd alone in 28-day cycles.
Daratumumab was administered at 20 mg / kg once a week for three weeks.
The recommended dose of daratumumab is 16 mg / kg intravenously.
Daratumumab has been shown to potently inhibit the in vivo growth of CD38-expressing tumour cells.
Daratumumab and R-CHOP were dosed simultaneously at day 0 or at 7 day interval.
Daratumumab which targets CD38 has been used in treating multiple myeloma.
