Examples of 'darifenacin' in a sentence
Meaning of "darifenacin"
Darifenacin is an adjective that pertains to a specific type of medication used to treat overactive bladder
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- A medication used to treat urinary incontinence.
How to use "darifenacin" in a sentence
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darifenacin
There are no human fertility data for darifenacin.
The active substance is darifenacin as hydrobromide.
Both these patients were randomised to receive darifenacin.
Darifenacin is excreted in the milk of rats.
It is not known whether darifenacin is excreted in human milk.
Darifenacin relieves spasms of the bladder.
Moderate hepatic damage caused extensive darifenacin retention.
Effects of darifenacin on other medicinal products.
Mild hepatic impairment had no effect on the pharmacokinetics of darifenacin.
Darifenacin hydrobromide is a substance which reduces the activity of an overactive bladder.
The active substance is darifenacin.
The pharmacokinetics of darifenacin have not been established in the paediatric population.
Emselex is a medicine that contains the active substance darifenacin.
Subsequently the darifenacin solution is separated from the resin by filtration.
Pharmaceutical formulations containing darifenacin.
See also
The hydrobromide salt of darifenacin has been the preferred compound for medical usage.
There are limited amount of data from the use of darifenacin in pregnant women.
Neither solifenacin nor darifenacin has a significant effect on heart rate compared with placebo.
The hydrate may be further elaborated to give an acid addition salt of darifenacin.
This invention relates to a new use of darifenacin and its pharmaceutically acceptable salts.
The darifenacin polystyrene sulphonate was then filtered off and washed until free of bromide ions.
This invention relates to pharmaceutical dosage forms of darifenacin and its pharmaceuticatty acceptable salts.
Lactation Darifenacin is excreted into the milk of rats.
Pregnancy There are no studies of darifenacin in pregnant women.
Characterization Darifenacin hydrobromide is a white to almost white crystalline powder.
EPAR summary for the public darifenacin.
Characterisation Darifenacin hydrobromide is a white to almost white crystalline powder.
Therefore, inhibitors of these enzymes may increase darifenacin exposure.
Paediatric patients The pharmacokinetics of darifenacin have not been established in the paediatric population.
Only a small percentage of the excreted dose was unchanged darifenacin 3.
However the data available do not indicate that darifenacin changes either midazolam clearance or bioavailability.
Accordingly, the present invention provides a stable solid hydrate of darifenacin.
Example Comparison of the effects of darifenacin and oxybutynin upon cognitive function in the elderly.
The effect of warfarin on prothrombin time was not altered when co-administered with darifenacin.
Pharmacokinetics Darifenacin is a lipophilic base.
Darifenacin treatment resulted in a modest increase in the exposure of the CYP3A4 substrate midazolam.
However, protein binding of darifenacin was affected by moderate hepatic impairment.
Darifenacin is a moderate inhibitor of the enzyme CYP2D6.
Prolonged-release ' means that darifenacin is released slowly from the tablet over a few hours.
A composition according to claim 4, wherein component ( b ) is darifenacin.
Food had no effect on darifenacin pharmacokinetics during multiple-dose administration of prolonged-release tablets.
Each tablet contains 15 mg darifenacin as hydrobromide.
Effects of darifenacin on other medicinal products CYP2D6 substrates.
At steady state, peak-to-trough fluctuations in darifenacin concentrations are small PTF.
In one embodiment, darifenacin is used as the muscarinic Inhibitor in the medicament.
Each tablet contains 15 mg darifenacin.
The metabolism of darifenacin in CYP2D6 poor metabolisers is principally mediated by CYP3A4.
In a preferred embodiment, the medicament contains from 2.5 milligrams to 30 milligrams of darifenacin.
In subjects who are poor metabolisers, darifenacin exposure increased approximately 10-fold.
Darifenacin is a lipophilic base and is 98 % bound to plasma proteins primarily to alpha-1-acid - glycoprotein.
