Examples of 'defensins' in a sentence
Meaning of "defensins"
defensins (noun) - Defensins are small proteins that are primarily known for their role in the immune system as antimicrobial agents, helping to defend the body against pathogens such as bacteria and fungi
Show more definitions
- plural of defensin
How to use "defensins" in a sentence
Basic
Advanced
defensins
Two different classes of defensins have been observed.
The defensins can be administered rectally vía a suppository.
Versatile functions of the defensins and cathelicidins.
Rabbit defensins were also cytotoxic to murine lymphomas.
In humans the predominant AMPs are the defensins.
Only alpha and beta defensins are expressed in humans.
Defensins have been isolated from insects and mammals.
Peptides may also belong to the class of defensins.
An imbalance of defensins in the skin may contribute to acne.
This may be accomplished by entrapping the defensins in liposomes.
Defensins are an essential component of the innate immune system.
Some of the specific defensins are more potent than others.
Defensins are generally cationic proteins.
It is widely accepted that defensins are important players in innate immunity.
The defensins can be utilized in aerosol formulation to be administered vía inhalation.
See also
Increasing evidence suggests the importance of defensins in the immune response.
Beta defensins have been shown to have activity in skin diseases.
The presence of defensins.
Cyclic beta defensins analogs for the treatment of infections.
Several species of insect produce antimicrobial peptides known as defensins and cecropins.
Defensins also inactivate viruses.
The precise physiological role of the enteric defensins is not clearly established.
Some defensins are synthesized as propeptides which may be relevant to this process.
Neutrophils release chemokines and defensins that are chemotactic for macrophages and lymphocytes.
Defensins are one of the most important classes of antimicrobial peptides in humans.
Alternative antibiotics such as human defensins and rabbit defensins lacked potent activity in this assay.
The defensins of the disclosure belong to the beta defensin class.
Human keratinocytes also secrete antimicrobial peptides such as cathelicidins and defensins with potential antifungal activity.
The defensins are one of the most studied classes of antimicrobial peptides.
The Aspergillus host cell may be used for recombinant production of insect defensins.
Defensins are preferably neutralized by inhibiting their interaction with lipid bilayers.
Depending on the content of hydrophobic amino acid residues Defensins also show haemolytic activity.
Defensins are examples of CAMPs.
Therefore, any combination of defensins and carriers are contemplated.
The defensins of the invention belong to the beta defensin class.
Taken together, these factors make natural defensins unsuitable for therapeutic applications.
Defensins are abundant antimicrobial peptide components of vertebrate neutrophil and macrophage granules.
For example, indolicidin peptides can be administered in conjunction with bactenecins, defensins or antibiotics.
The defensins used may be of the same or different types and subtypes.
Plectasin has a chemical structure resembling defensins found in spiders, scorpions, dragonflies and mussels.
Defensins play an important role in preventing infections and safeguarding the immunity of epithelial tissues.
Table 1 below shows an exemplary cosmetic delivery liposome formulation including two types of defensins.
The defensins have also been demonstrated to exhibit substantial in vitro cytotoxicity toward mammalian cells.
They also identified six novel tick defensins ( defence peptides ) with promising antimicrobial activity.
The defensins also share six conserved cysteine residues that participate in intramolecular disulfide bonds.
These granules contain a mixture of antimicrobial molecules including various peptides such as the so-called defensins.
Defensins are antibiotics made from peptides and are typically found in animals and higher plants.
The present inventors have identified peptides that, surprisingly, have improved antimicrobial activity over natural defensins.
Defensins and Prodefensins are therefore to be considered as two different proteins.
A reduction of ileal defensins may predispose to Crohn 's disease.
