Examples of 'degranulation' in a sentence
Meaning of "degranulation"
Degranulation (noun): the process by which granules from cells, such as mast cells or neutrophils, are released into the surrounding tissue or bloodstream
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- The loss of secretory granules in certain cells
How to use "degranulation" in a sentence
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degranulation
Degranulation and secretion were measured by separate methods.
Compounds of the invention are expected to inhibit degranulation.
Degranulation is an active process and requires energy.
It inhibits the degranulation of mast cells.
There is described a method of inhibiting mast cell degranulation.
Inhibition of the degranulation of human basophiles.
Activation of basophils includes proliferation and degranulation of basophils.
Activation of mast cell degranulation by IgE interaction with FcεRI.
Degranulation of basophils is not present using blood of healthy donors.
Incubation of cells for degranulation assays.
The degranulation process is stopped by incubating the blood samples on ice.
It is released when neutrophils undergo degranulation during activation.
Degranulation was measured as follows.
The apoprotein is released on degranulation of the PMNs in septic areas.
This drug was shown to inhibit rodent mast cell degranulation.
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The subsequent neutrophil degranulation may result in epithelial cell damage.
The following treatments were used to induce mast cell degranulation.
VÃa the degranulation process.
Pelorol significantly reduced IgE induced mast cell degranulation.
Allergen contact causes degranulation of mucosal mast cells and histamine is released.
These results again indicate a direct degranulation of mast cells.
Percent degranulation is calculated as the percentage of serotonin released out of the total incorporated.
Very small amounts of them are required to trigger mast cell degranulation.
It has an essential role in mast cell degranulation and cytokine production.
The invention further provides a method of inhibiting mast cell degranulation.
Histamine is a mediator released during degranulation of immune cells of the mastocytes or basophilic type.
During allergic inflammation these complexes are released vÃa mast cell degranulation.
The effect is thus caused by a direct degranulation of mast cells causing histamine release.
Lower levels of dehydroepiandrosterone showed proportionately less capacity to inhibit degranulation.
The ability of a particular substance to inhibit mast cell degranulation can be readily determined empirically.
Following receptor activation of a variety of preformed chemical mediators and agents vÃa degranulation.
The ability of these molecules to inhibit mast cell degranulation in vitro was also tested.
Leukocyte granules are released in response to immunological stimuli during a process known as degranulation.
Inhibitors of mast cell activation and degranulation prevent the release of proinflammatory mediators and cytokines.
Activation of dendritic cells includes proliferation and degranulation of dendritic cells.
Degranulation of human leukocytes is also inhibited by MANS.
Analysis of the inflammatory process on the basis of mast cell degranulation counts.
ECP is released during degranulation of eosinophils.
The monomeric allergens would not trigger mast cell or basophil degranulation.
The degranulation process in a Mast cell.
Heparin is found within mast cell granules and is released upon degranulation.
COPs do not induce basophil degranulation at any tested concentration.
The damage to the gastrointestinal tract wall is caused by eosinophilic infiltration and degranulation.
Spontaneous degranulation of SHR neutrophils is also detectable with myeloperoxidase measurements.
Histamine is also only one of many mediators produced during mast cell degranulation.
Activation and degranulation by platelets is also mediated by the Syk pathway.
The number above the bar corresponds to the mean percentage inhibition of degranulation.
Results Effect of goblet cell degranulation by fMLP on nasal epithelial structure.
The present invention also provides a method for inhibiting the degranulation of mast cells.
PAF causes the aggregation and degranulation of platelets at very low concentrations.
