Examples of 'dicyclohexylcarbodiimide' in a sentence
Meaning of "dicyclohexylcarbodiimide"
dicyclohexylcarbodiimide (adjective): Describing a chemical compound often used in organic synthesis, particularly in peptide synthesis. It acts as a coupling reagent to form amide bonds between amino acids
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- The di-cyclohexyl derivative of carbodiimide that is used in peptide synthesis
How to use "dicyclohexylcarbodiimide" in a sentence
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dicyclohexylcarbodiimide
In the presence of dicyclohexylcarbodiimide and dimethylaminopyridine in tetrahydrofuran.
An organic solvent in the presence of hydroxysuccinimide and dicyclohexylcarbodiimide.
Dicyclohexylcarbodiimide is used as the coupling reagent.
Further examples include dicyclohexylcarbodiimide and the like.
Dicyclohexylcarbodiimide may be mentioned by way of example.
An aqueous solution in the presence of hydroxysuccinimide and dicyclohexylcarbodiimide.
Dicyclohexylcarbodiimide is preferably used.
It is the byproduct of the reaction of dicyclohexylcarbodiimide with amines or alcohols.
The coupling agents used in the reaction is selected from hydroxybenzotriazole and dicyclohexylcarbodiimide.
In an organic solvent in the presence of dicyclohexylcarbodiimide as said condensing agent.
The coupling agent used in the reaction is selected from hydroxybenzotriazole and dicyclohexylcarbodiimide.
Examples of the condensing agent include dicyclohexylcarbodiimide and polyphosphoric acid.
The dicyclohexylcarbodiimide was from Aldrich and was distilled in vacuo before use.
That process has disadvantages related to use of the dicyclohexylcarbodiimide.
DCC dicyclohexylcarbodiimide The invention is illustrated by the following examples.
See also
Examples of other activating agents include dicyclohexylcarbodiimide or thionyl chloride.
If dicyclohexylcarbodiimide is used, it should be employed with an acid source.
Further examples include dicyclohexylcarbodiimide.
Two examples are dicyclohexylcarbodiimide and triphenylphosphine / diethyl azodicarboxylate.
The reagent for condensation of both crucial intermediates was dicyclohexylcarbodiimide.
BOC protected aminoacids were activated by using dicyclohexylcarbodiimide and introduced as hydroxybenzotriazoles esters.
Esterification with p-nitrophenol was performed in the presence of dicyclohexylcarbodiimide.
Even so methanediimines, especially dicyclohexylcarbodiimide may be used as cyclodesulfurizing agents.
Method according to claim 5, wherein the carbodiimide is dicyclohexylcarbodiimide.
Also methanediimides, especially dicyclohexylcarbodiimide may be used as cyclodesulfurizing agents.
In general, the condensing agent is a carbodiimide such as dicyclohexylcarbodiimide.
Preferably, the dehydrating agent is dicyclohexylcarbodiimide and the alcohol is hydroxybenzotriazole.
Dehydrating agents which may be mentioned are carbodiimides, in particular dicyclohexylcarbodiimide.
Other coupling agents, such as dicyclohexylcarbodiimide can be used.
Appropriate activating agents include carbonyldiimidazole, diethylphosphoryl cyanide and dicyclohexylcarbodiimide.
In these reactions standard condensation reagents such as dicyclohexylcarbodiimide or ethyl chloroformate may be employed.
Of those, dicyclohexylcarbodiimide and diisopropylcarbodiimide are particularly preferable because of their industrial availability.
This reaction can be carried out in pyridine using dicyclohexylcarbodiimide as a condensing agent.
Further, dicyclohexylcarbodiimide and the like may also be used as an organic dehydrating agent.
As the dehydration condensation agent, dicyclohexylcarbodiimide is preferred.
In a preferred embodiment, the esterification of step b is performed with a carbodiimide preferentially dicyclohexylcarbodiimide.
The dehydrating agent includes, for example, dicyclohexylcarbodiimide or carbonyldiimidazole.
A monophosphate may be converted to a cyclic phosphate using a dehydrating agent, such as dicyclohexylcarbodiimide.
For example, carbodiimides such as dicyclohexylcarbodiimide can be preferably used as such reagents.
Method according to claim 8, in which the coupling activator is dicyclohexylcarbodiimide.
Dehydrating agents, for example, dicyclohexylcarbodiimide or molecular sieves can also be used.
Alternatively, this reaction can be accomplished using a coupling reagent such as for example dicyclohexylcarbodiimide.
In addition, diimides other than dicyclohexylcarbodiimide can also be employed with similar results.
Suitable dehydrating agents include acetic anhydride, phosphorus pentoxide, dicyclohexylcarbodiimide and acetyl chloride.
Dicyclohexylcarbodiimide ( DCC ) and structural analogs are also suitable linkers.
The method of claim 5, wherein said method comprises a dicyclohexylcarbodiimide condensation.
A solution of dicyclohexylcarbodiimide ( 6mmol ) in dry dichloromethane was added to the mixture dropwise with stirring.
Examples of the dehydration condensation agents include, for example, carbodiimide derivatives such as dicyclohexylcarbodiimide.
Reaction of 5 with acyclovir monophosphate and dicyclohexylcarbodiimide in pyridine will lead to the target compound.
This material was dissolved in ethyl acetate and treated with 4-methylpentanoic acid followed by dicyclohexylcarbodiimide.
