Examples of 'dimerization domain' in a sentence
Meaning of "dimerization domain"
dimerization domain: In molecular biology, a dimerization domain is a structural motif within a protein that allows two identical or similar molecules to bind together, forming a dimer. This interaction is important for various cellular processes and signaling pathways
How to use "dimerization domain" in a sentence
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dimerization domain
Preferably modifications are made within a dimerization domain.
In other embodiments the dimerization domain is a single cysteine.
The dimerization domain has a hinge region in some embodiments.
Such cysteines are preferably located in a dimerization domain of a monomer.
The dimerization domain may comprise a leucine zipper sequence.
The multivalent antibody can comprise a dimerization domain and three or more antigen binding sites.
A dimerization domain can be a polypeptide capable of inducing interaction or association of two polypeptides.
In one embodiment, the interaction domain is a dimerization domain.
It is a common dimerization domain found in some proteins involved in regulating gene expression.
Optionally, a polypeptide of the invention further comprises a dimerization domain.
This site locks the dimerization domain and increases the dimer stability.
Accordingly, in some embodiments, a polypeptide of the invention further comprises a dimerization domain.
The preferred dimerization domain includes an Fc region or a hinge region.
Preferably, such modifications occur in the dimerization domain of the fragment.
The most preferred dimerization domain herein is an Fc region or a hinge region.
See also
The leucine zipper is a super-secondary structure that functions as a dimerization domain.
In particular, the dimerization domain may be a leucine zipper.
For display of the polypeptides in bivalent manner, the fusión protein preferably includes a dimerization domain.
Dimerization domain mutations in the cleavage half-domain.
Preferably, such modification occurs in the dimerization domain of the tRNA synthetase fragment.
The dimerization domain of AtE2Fs appears to be sufficient for binding to AtDPs.
Figure 33 shows one representative mass spectrum of estrogen receptor dimerization domain desorbed from this surface.
The preferred dimerization domain comprises ( or consists of ) an Fc region or a hinge region.
In further embodiments, the CTLA4 peptide can be fused to a peptide dimerization domain.
The protein contains a hAT dimerization domain nears its C-terminus.
In particular, the targeting ligand is a fusión protein comprising a P-selectin ligand and a dimerization domain.
In some embodiments, the dimerization domain comprises at least a portion of the Fc fragment.
Binding of AtDPb to AtE2Fb, however, only requires an intact AtDPb dimerization domain.
The mouse IgG2a Fc is used both as a dimerization domain and to provide effector functions.
The dimerization domain comprises ( or consists of ), for example, an Fc region or a hinge region.
These complexes could be a result of the dimerization domain in the Gal4 DNA-binding region.
Plant E2F dimerization domain with or without ( part of ) the marked box.
The results noted for pTOX5-GCN4 demonstrate that a foreign dimerization domain can restore inducible activation.
The dimerization domain is localized to the first 32 amino acids of the HNF 1a proteins.
The CTLA4 peptide can be fused to a peptide dimerization domain or an immunoglobulin ( Ig ) molecule.
Plant DP dimerization domain with or without ( part of ) the C-terminal DP domain.
Optionally, heavy chains of the F ( ab ) 2 dimerize at a dimerization domain not including a hinge region.
In Fig . 4B, the dimerization domain of the tetravalent antibody is an Fc region.
Each Hsp90 has an ATP-binding domain, a middle domain, and a dimerization domain.
In one embodiment, the dimerization domain is that of a basic region leucine zipper ( “ bZIP ” ).
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Dimerization is a side reaction that can occur
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