Examples of 'dominant negative' in a sentence
Meaning of "dominant negative"
dominant negative ~ In grammar or linguistics, the term 'dominant negative' refers to a negative element in a sentence that has a greater impact or influence on the sentence's meaning compared to other negative elements present
How to use "dominant negative" in a sentence
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dominant negative
Such mutations are termed dominant negative mutations.
A dominant negative effect of one of these mutations was shown.
This may lead to dominant negative effects.
Dominant negative is a polypeptide antagonist of an oncogenic signalling pathway.
Such peptides are known as dominant negative mutant proteins.
The dominant negative protein can be produced synthetically.
Identification of heteromeric receptors and a dominant negative mutant.
Politics as a dominant negative mutation.
Dominant negative transgenes are constructed according to methods known in the art.
Other useful mutations include dominant negative mutants.
The dominant negative protein may be administered as an expression vector.
Disruption of dominant negative alleles.
Dominant negative selection markers for positive identification of deletion derivatives.
Thus attC and attG mutations are dominant negative mutations.
Such dominant negative forms are also contemplated according to the invention.
See also
Marfan syndrome is also an example of dominant negative mutation and haploinsufficiency.
Deletion or domain swapping techniques can also be employed to create a dominant negative mutant.
Expression of a dominant negative phospholamban decreases damage in failing cardiac cells.
An antisense or cosuppression construct would act as a dominant negative regulatory of gene activity.
The concept of a dominant negative ethylene receptor is well known in the art.
An antisense or cosuppression construct would act as a dominant negative regulator of gene activity.
The concept of a dominant negative transcription factor is also well described in the art.
The latter method is for example downregulation through a dominant negative approach.
Expression of dominant negative phospholamban disrupts the function of the wild type protein.
Another means of inhibiting gene function in a plant is by creation of dominant negative mutations.
The dominant negative regulation available with a transgenic approach may be advantageous from a breeding perspective.
Theoretically a vir mutant may arise due to a dominant negative mutation in the repressor protein gene.
The dominant negative regualtion available with a transgenic approach may be advantageous from a breeding perspective.
The signal can be blocked by a dominant negative mutant of CAML.
Dominant negative PLB mutant for use in treating cardiac disease.
A GCRA peptide may include dominant negative forms of a polypeptide.
Dominant negative effect of UBCh5 mutants.
Examples of such mutants include dominant negative mutants of a MAP gene.
By way of example, two mutations could possibly be synthetically dominant negative.
A corresponding mutation in HAAH is used as a dominant negative mutant to inhibit HAAH hydroxylase activity.
The indehiscent phenotype can be accomplished using an anti-sense or a dominant negative approach.
The PYY antagonist can be a dominant negative form of a PYY polypeptide.
In some embodiments, the mutation is a loss of function or a dominant negative mutation.
This phenomenon is called the dominant negative effect and is observed in many p53 mutations.
The mutant CKI polypeptides of the present invention are dominant negative proteins.
Expressing a dominant negative DA1 polypeptide within cells of said plant.
A further method for blocking said VGSC activity includes dominant negative suppression.
A dominant negative construct also can be used to suppress IND1 expression in a plant.
Antibodies, decoy receptors and dominant negative receptors.
The dominant negative protein can be a splice variant of TLR3 or fragments thereof.
Mutations, fragments and fusions are also useful as dominant negative mutations.
Also, dominant negative mutants of PML may be used to inhibit the immune response.
In addition, variants can be those that encode dominant negative mutants as described below.
Several dominant negative mutations were also identified, including two C terminal truncations.
Methods for inhibiting glucanase activity, may use dominant negative mutants or anti-glucanase antibodies.
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The dominant economic model has failed
Women as presidents were dominant in the cantonal courts
The dominant component of those operations is mining
Examples of using Negative
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Dissolution of etheric negative etheric or astral objects
Negative test results would also be recorded
Suitable for extended negative pressure service
