Examples of 'doripenem' in a sentence
Meaning of "doripenem"
Doripenem is a noun that refers to a type of antibiotic used to treat various bacterial infections. It belongs to the carbapenem class of antibiotics
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- An injectable carbapenem antibiotic.
How to use "doripenem" in a sentence
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doripenem
Each vial contains doripenem monohydrate equivalent to.
Doripenem is primarily eliminated unchanged by the kidneys.
Doribax contains the active substance doripenem.
It is unknown whether doripenem is excreted in human breast milk.
Doripenem is a synthetic carbapenem antibacterial agent.
Doribax is a medicine containing the active substance doripenem.
Doripenem has a spectrum of activity very similar to that of meropenem.
The active substance is doripenem.
The medium containing doripenem is therefore superior to the commercial medium.
If you are allergic to doripenem.
Doripenem exerts its bactericidal activity by inhibiting bacterial cell wall biosynthesis.
A study in rats has shown that doripenem and its metabolite are transferred to milk.
Doripenem is also more active against Pseudomonas aeruginosa than other carbapenems.
Hepatic Impairment The pharmacokinetics of doripenem in patients with hepatic impairment have not been established.
Species resistant to other carbapenems do generally express co-resistance to doripenem.
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In vitro doripenem showed little potential to antagonize or be antagonized by other antibacterial agents.
What is Doripenem.
In vitro doripenem showed little potential to antagonise or be antagonised by other antibacterial agents.
Methicillin-resistant staphylococci should always be considered as resistant to doripenem.
The effect of race on doripenem pharmacokinetics was examined through a population pharmacokinetic analysis.
All methicillin-resistant staphylococci should be regarded as resistant to doripenem.
The pharmacokinetics of doripenem in patients with hepatic impairment have not been established.
What Doribax contains - The active substance is doripenem.
Probenecid competes with doripenem for renal tubular secretion and reduces the renal clearance of doripenem.
Infuse all of this solution to administer a 500 mg dose of doripenem.
Mode of action Doripenem is a synthetic carbapenem antibacterial agent.
If you are allergic ( hypersensitive ) to doripenem.
Therefore, doripenem should not be administered by this route.
The rash resolved within 10 days after doripenem administration was discontinued.
However, doripenem has not been proven to possess polymorphism.
Infuse all of the remaining solution to administer a 250 mg dose of doripenem.
Doripenem is metabolized by the enzyme dehydropeptidase-I into an inactive ring-opened metabolite.
Should a hypersensitivity reaction to doripenem occur, it should be discontinued immediately and appropriate measures taken.
Doripenem is moderately soluble in water, slightly soluble in methanol, and virtually insoluble in ethanol.
Seizures have been reported during treatment with carbapenems, including doripenem see section 4.8.
Metabolism of doripenem to a microbiologically inactive ring-opened metabolite occurs primarily via dehydropeptidase-I.
Beta-lactamases ( such as penicillinases ) formed by gram-positive and gram-negative bacteria can stabilize doripenem to hydrolysis.
Doripenem appears as crystalline powder, with colour anywhere from a white to somewhat yellowish.
Each vial contains 250 mg doripenem as monohydrate.
Unlike meropenem, doripenem is not approved for the treatment of other serious hospital-acquired infections.
Doribax 500 mg powder for solution for infusion doripenem.
Each vial contains doripenem monohydrate equivalent to 500 mg doripenem.
Doribax 500 mg powder for infusion doripenem Intravenous use.
Doripenem inactivates multiple essential penicillin-binding proteins ( PBPs ) resulting in inhibition of cell wall.
In an interaction study, the mean doripenem AUC increased by 75 % following co-administration with probenecid.
Doripenem AUC increased 49 % in elderly adults relative to young adults.
The concomitant use of doripenem and valproic acid / sodium valproate is not recommended see section 4.5.
Doripenem ( Doribax, Finibax ) is an antibiotic drug in the carbapenem class.
Doripenem AUC was 15 % higher in females compared to males.
