Examples of 'double mutant' in a sentence
Meaning of "double mutant"
The term 'double mutant' is used in the field of virology or genetics to describe a variant or strain of a virus that has two significant mutations in its genetic makeup. These mutations may impact the transmissibility, severity, or immune response of the virus. The term gained prominence during the COVID-19 pandemic to describe certain strains of the SARS-CoV-2 virus with multiple mutations
How to use "double mutant" in a sentence
Basic
Advanced
double mutant
The double mutant is auxotrophic for methionine.
Success at this attempted mutation would obviously lead to a double mutant.
The double mutant is not susceptible to further activation.
The ability to colonise the rhizosphere was also significantly compromised in the double mutant.
The double mutant lacked expression of either protein.
The following construct was prepared to test the double mutant vaccines in an animal model.
This double mutant also shows a substrate inhibition effect.
Progeny must be self pollinated to produce the necessary homozygous recessive double mutant plants.
Growls of this double mutant was severely affected even in the presence of oxygen.
Briefly, blastocysts were generated by natural matings of homozygous double mutant mice.
The double mutant does not retain the capability for further activation.
The engineered thioesterase of claim 1, wherein said engineered thioesterase is a double mutant.
The double mutant fap tlb combines the features of tlb and fap.
Complementation tests on MMS-media identified double mutant strains from many intercrosses.
This double mutant strain was used for derivation of ES cells.
See also
Restoration of heart functions occurred in both male and female ace-ace2 double mutant mice.
The lack of phenotype in the double mutant suggested that another kinase provides redundant function.
The exemplified compounds have activity against HIV WT, single and double mutant strains.
The immune response of the double mutant mice to Listeria monocytogenes is normal.
Next, two additional genes, yncB and ydjA, were depleted in the yjgB yahK double mutant.
This double mutant was the result of an in vitro Klenow DNA polymerase reaction mistake.
The amino acid sequence of the double mutant is disclosed in SEQ ID No 8.
These double mutant mice were born at the expected Mendelian ratio and appear healthy.
Phenotype of the au hp-2 double mutant phenotype.
This double mutant is therefore more attenuated than either the vaccine strain or mutant 7.
To test this notion, acelace2 double mutant mice were generated.
Atrbohd / f double mutant plants failed to induce the antioxidant response under the culture conditions.
Fertility of the ace-ace2 double mutant mice was not addressed.
The double mutant was used in a dye-terminator sequencing reaction with fluorescein-labeled dye terminators.
The method of 39 wherein the Thermococcus sp is 9°N or a single mutant or double mutant thereof.
As indicated, neither double mutant caused lethality in the rabbits.
In contrast, collagen deposition was dramatically increased in the double mutant lungs ( Figure 8B ).
We therefore used the fab1 / fael double mutant as an experimental host for subsequent experiments.
A double mutant tat gene, constructed by D. Clements ( Tulane University ) was selected for these constructs.
Thus, the infection with the double mutant resulted in long lasting immunological memory.
To determine this, researchers will identify so-called " synthetic lethal double mutant combinations . ".
In the double mutant case, both the electrostatic interactions favor heterodimer and disfavor homodimer formation.
Figure 9 provides an electrospray MS analysis of the full-length double mutant protein ( produced in Figure 7B ).
Putative double mutant lines were verified by DNA polymorphisms for both Abi3 and Era1.
Notably, the severity of renal lesions was substantially reduced in double mutant jck/Lcn2 - / - mice.
The double mutant was selected on a solid minimal medium containing 1 % carboxymethyl-cellulose as main carbon source.
Soybean codon-optimized version of double mutant soybean EPSPS cDNA cSpec-03.
The double mutant construct is about 5-fold more effective than unmodified GUS.
These hybrid plasmids were used to retransform the double mutant Streptomyces lividans 10-164.
In this way a double mutant ( mannose PTS and glucokinase ) was isolated.
Preferably, however, the selected plant is a double mutant for DFR and F3 ' H.
The double mutant ( M4 ) hence exhibited the strongest reduction of IgE binding capacity.
However, the A mnn6 Amnn4 double mutant does not further reduce this activity.
A double mutant comprising both the R44Q and F50A substitutions was constructed.
Thus, the BoNT / A-L chain double mutant fusión protein was devoid of enzymatic activity, as expected.
You'll also be interested in:
Examples of using Double
Show more
No double talk and nobody gets hurt
Select a folder and double tap to open it
Double time and down to the quad
Examples of using Mutant
Show more
That little mutant would be lucky to have me
How can the appearance of one mutant
An unidentified mutant yet in the academic world
