Examples of 'down-regulated' in a sentence
Meaning of "down-regulated"
Down-regulated - (verb) In the field of biology or genetics, it refers to the process of decreasing or reducing the expression or activity of a gene, protein, or biological process within a cell or organism
How to use "down-regulated" in a sentence
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down-regulated
Growth signals are down-regulated by this internalization.
Expression of vinculin in muscle cells was strikingly down-regulated.
These genes are down-regulated in relapsers.
We identified a tumor gene signature that contained up - and down-regulated microRNAs.
The protein appears to be down-regulated during bladder cancer progression.
Several of the oligonucleotides significantly down-regulated progerin.
Immune reactivity is normally down-regulated when the eliciting antigenic structures are eliminated.
Leukocyte cell adhesion molecules mobilization was not down-regulated on granulocytes ;.
Dexamethasone also down-regulated anti apoptotic genes and increased IκB-α protein levels.
In an embodiment, expression or function is down-regulated as compared to a control.
The reporter gene can also be a endogenous yeast gene which is up - or down-regulated.
In an instance, expression or function is down-regulated as compared to a control.
The receptors on cells become less sensitive to the hormone or down-regulated.
Metal-specific lymphocyte reactivity is down-regulated after dental metal replacement.
In another embodiment, the reactivity of at least one antibody to a specific antigen is down-regulated.
See also
In another embodiment, expression or function is down-regulated as compared to a control.
In additional embodiments, the reactivity of at least one antibody to a specific antigen is down-regulated.
In another instance, expression or function is down-regulated as compared to a control.
In females, vinclozolin down-regulated expression of estrogen receptors and up-regulated progesterone receptor expression.
Studies show that negative mood is down-regulated overnight.
The up-regulated and down-regulated genes involved in cellular assembly and organization are shown.
This is because the serotonin can not bind to down-regulated receptors.
It has been shown that it was down-regulated in selectively vulnerable regions of AD brain.
After sodium depletion, mesenteric artery angiotensin II receptors were down-regulated as expected.
In another embodiment, telomerase activity is down-regulated by antisense oligonucleotides binding to promoter sequences.
These results suggest that transcription from the RSV LTR is down-regulated by Rep.
Examples of microRNAs which are down-regulated in brain tumor are provided in Table 9.
Such genes can either be up - or down-regulated.
MiRNAs that are down-regulated in cancers could be useful as anticancer agents.
It is known for example, that autophagy is naturally down-regulated as a result of normal ageing.
Cdc6 is down-regulated rapidly during quiescence and differentiation.
The expression of the respective gene can thus be down-regulated or completely abolished.
All transcripts that were down-regulated by these criteria demonstrated upregulation in HSALR mice.
With repeated pressing of the button, the level is down-regulated until it switches off.
GcMAF also down-regulated the over-activation of BMDMs from.
The fibroblast-specific markers vimentin and fibronectin were down-regulated in the reprogrammed cells.
MiR-9 is specifically down-regulated in a model of spinal muscular atrophy.
In ob / ob obese mice, the expression of adipoQ was down-regulated.
SATB2 was found significantly down-regulated but was not selected for any further analysis.
During chondroblast differentiation, RARa expression is down-regulated.
Cluster b3 identifies genes down-regulated in both localized PCA and metastatic PCA.
Preferably, the level of inflammatory cytokines is down-regulated.
The myocardin and SMMHC maybe down-regulated in response to a thromboxane A2 mimetic.
During hematopoietic cell differentiation, this gene is down-regulated.
In this manner up - and down-regulated genes may be determined.
For example, cellular protein synthesis may be significantly down-regulated.
Then, the subject showing down-regulated expression is selected.
Moreover, half of them are up-regulated while the other half are down-regulated.
They may protect against or fail to protect ( if down-regulated by an infection ) against cancers.
Both aquaporin gene and protein expression can be up-regulated or down-regulated.
