Examples of 'dsrnas' in a sentence
Meaning of "dsrnas"
dsrnas (noun) - Double-stranded RNA molecules that play a role in various biological processes such as gene regulation and antiviral defense mechanisms
Show more definitions
- plural of dsRNA
How to use "dsrnas" in a sentence
Basic
Advanced
dsrnas
The dsRNAs can be linear or circular in structure.
The serum stabilities of each of the following dsRNAs were analyzed.
Hairpin dsRNAs are typically referred to as shRNAs.
Discloses liposomes comprising dsRNAs targeted to the raf gene.
These dsRNAs can be introduced to an individual cell or culture system.
The oocyte may be modified using one or more dsRNAs.
Later it was found that dsRNAs can also act as saRNA.
The dsRNAs may be expressed using a single promoter or multiple promoters.
This finding suggests that dsRNAs occur commonly in rust fungi.
A variety of different bacterial hosts may be used to produce insect control dsRNAs.
The compositions of dsRNAs and nucleic acids may be formulated as microemulsions.
Therapeutic intervention for such conditions with dsRNAs is also described.
One promising potential of dsRNAs is its immunomodulating effect in antimicrobial therapies.
Base analogs can duplex with other bases or base analogs in dsRNAs.
The exact length of the long dsRNAs is indicated below the bars.
See also
Targeted dsRNAs frequently accumulate in endosomes from which they need to escape to be active.
Stability of dsRNAs.
The region targeted by the dsRNAs are indicated as black bars on both sides.
Tests were undertaken to determine the role or phenotype associated with the presence of dsRNAs.
We show that such long dsRNAs mediate RNAi in a variety of cell types.
The cleavage sites are all located within the region of identity of the dsRNAs.
Indeed the use of relatively short homologous dsRNAs may have certain advantages.
The dsRNAs described therein generally are suitable for use according to the present invention.
Northern blot analysis indicates the presence of siRNAs corresponding to the dsRNAs used in treatment.
Such chemically linked dsRNAs are suitable for packaging in the association complexes described herein.
Summary of data for five most potent TTR dsRNAs.
DsRNAs as used herein are understood to include siRNAs.
Sense and antisense strand sequences of human TTR dsRNAs.
DsRNAs are rather stable in biological media.
Comparison of the efficiency of RNAi between long dsRNAs Fig.
DsRNAs targeting gene promoters induce potent transcriptional activation of associated genes.
Chemically modified sense and antisense strand sequences of human TTR dsRNAs.
It is expected that the nicked dsRNAs possessing a tetraloop exhibit enhanced cleavage by Dicer.
Chemically modified sense and antisense strand sequences for rat TTR dsRNAs.
It is expected that the nicked dsRNAs with a tetraloop have enhanced cleavage by Dicer.
Identification numbers for human TTR dsRNAs.
Cells were transfected with dsRNAs corresponding to either cyclin E or lacZ.
DsRNAs are typically used to mediate RNA interference.
EXAMPLES Identification of dsRNAs for therapeutic use.
Therefore, dsRNAs control gene expression via sequence complementarity.
Accordingly, siRNA may be affected by introduction or expression of relatively short homologous dsRNAs.
Thus, the dsRNAs can be fully or partially double stranded.
Knock-down of gene expression can be directed by the use of dsRNAs or siRNAs.
Alternatively, dsRNAs may be complexed to lipids, in particular to cationic lipids.
This may be particularly advantageous when formulating thermolabile drugs, peptides or dsRNAs.
Alternatively, already annealed dsRNAs may be purchased from the suppliers.
The dsRNAs of the present invention can be used in gene-silencing.
In one implementation, the compositions of dsRNAs and nucleic acids are formulated as microemulsions.
Also, dsRNAs could persist for a long time in the environment.
Graphic representation of dsRNAs used for targeting Pp-luc mRNA.
