Examples of 'dystrophin' in a sentence
Meaning of "dystrophin"
dystrophin (noun) - A protein found in muscle cells that helps stabilize and protect muscle fibers. Mutations in the gene that encodes dystrophin can lead to muscular dystrophy, a group of genetic diseases characterized by progressive muscle weakness and degeneration
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- A cytoplasmic structural protein that is deficient in some forms of muscular dystrophy
How to use "dystrophin" in a sentence
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dystrophin
Muscles lacking dystrophin develop less tension.
The name is a contraction for ubiquitous dystrophin.
The subject may be a dystrophin deficient subject.
Utrophin is functionally and structurally similar to dystrophin.
The loss of dystrophin leads to the secondary.
Previous attempts at correctly expressing dystrophin have failed.
Precisely how dystrophin functions is far from clear.
The polypeptide may contain no epitope found in dystrophin.
The human dystrophin is located beneath the sarcolemma.
Molecular therapies for dystrophin deficiency.
Dystrophin contains multiple functional domains.
This disease affects dystrophin in the muscle cell.
Utrophin is a protein structurally and functionally similar to dystrophin.
Hippo and dystrophin complex signaling in cardiomyocyte renewal.
The cells were subjected to immunofluorescence for dystrophin as follows.
See also
Dystrophin is a long filamentous protein essential to skeletal muscle function.
Simultaneous skipping of multiple dystrophin exons.
The dystrophin gene is the largest gene identified to date.
It is caused by a mutation in the gene for the protein dystrophin.
The size of the dystrophin protein is indicated on the side.
Sarcolemmal instability due to mutations in dystrophin has a cascade effect.
Dystrophin plays a massive role in keeping the body healthy.
Also get a muscle biopsy and dystrophin of the daughter.
Dystrophin and titin are two large proteins causing muscular dystrophies.
Encodes a functional dystrophin protein.
Dystrophin plays an essential role in maintaining the integrity of muscle cells.
An individual is provided with a functional dystrophin protein in various ways.
Cells regenerated from these edited cells successfully produced dystrophin.
Said skeletal muscle may comprise dystrophin deficient skeletal muscle.
This genetic defect prevents the gene from producing dystrophin.
Coincidence of early dystrophin loss and the transition of compensated to decompensated hypertrophy.
Preferably said cells comprise a gene encoding a mutant dystrophin protein.
Making the dystrophin protein from the gene involves several steps.
Western blot analysis confirmed the presence of dystrophin in varying amounts.
The dystrophin intensities were typically lower than those in a healthy muscle biopsy.
Scientists have created a gene that produces small amounts of dystrophin.
Substitution of dystrophin domains with those of utrophin may lower immune responses.
It is a progressive muscle disorder caused by the lack of functional dystrophin protein.
Many different mutations in the dystrophin gene can lead to a dysfunctional protein.
Said nucleic acid sequence could encode all or part of dystrophin.
This shortened dystrophin protein mimics a mild phenotype dystrophin as mentioned above.
Exon skipping resulted in high levels of expression of dystrophin in the treated muscles.
Dystrophin crosslinks and stabilizes the muscle cell membrane and cytoskeleton.
Duchenne muscular dystrophy occurs when that gene fails to make dystrophin.
Mutations in the dystrophin gene result in a failure to produce dystrophin in striated muscles.
Most types of muscular dystrophy are caused by the deficiency of a protein known as dystrophin.
Two strategies that both aimed to stabilize dystrophin expression were explored here.
Duchenne muscular dystrophy does occur when the gene fails to make dystrophin.
The protein is colocalized with both dystrophin and dystroglycan at the ribbon synapses.
This allows the body to make a working form of the dystrophin protein.
