Examples of 'e-cadherin' in a sentence
Meaning of "e-cadherin"
e-cadherin (noun): A specific type of protein found in cells that plays a role in cell adhesion. This term is used in scientific or medical contexts, particularly in studies related to cell biology or genetics
How to use "e-cadherin" in a sentence
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e-cadherin
E-cadherin underexpression has been implicated in mammary tumor invasiveness.
Loss of function or decreased expression of e-cadherin may lead to cancer progression and metastasis.
E-cadherin is also used by pathologists to diagnose different kinds of breast cancer.
The cells have been immunolabeled for E-cadherin.
This is also why e-cadherin is considered an important tumour suppressor molecule.
A monoclonal antibody which is directed against E-cadherin was used for counterstaining.
E-cadherin mediates cell ¿ cell adhesion by being an essential component of the intercellular adhesion complexes.
This soluble form corresponds to the cleavage of the extracellular portion of E-cadherin.
Several studies show that e-cadherin could be important in inhibition of cell proliferation.
Another useful marker for the pluripotent cells of the invention is E-cadherin.
E-cadherin alongside other molecules served for the diagnosis and prognosis of cancer.
He or she may also order a special test called an E-cadherin protein study.
E-cadherin is a crucial type of cell-cell adhesion to hold the epithelial cells tight together.
The Snail transcription factor has been identified as a repressor of the expression of E-cadherin.
Structure of E-cadherin binding with heavy metals was also investigated.
See also
Adhesion is mediated by interaction between extracellular domains of E-cadherin dimers on adjacent cells.
We then examined E-cadherin expression in hESCs after trypsin dissociation.
A preferred antigen that is highly specific to a surface receptor on epithelial cells in E-cadherin.
Thus, reintroducing E-cadherin expression reverts carcinomas to a less advanced stage.
The risk factors are undefined, except for rare inherited mutations in E-cadherin.
E-cadherin was used as sample loading control for the Western blot.
The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells.
Identified E-cadherin transcript variants arise from mutation at consensus splice sites.
In breast carcinoma dysadherin expression is correlated with invasiveness but not with E-cadherin.
Loss of E-cadherin expression is envisioned as a key event in the epithelial-mesenchymal transition.
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression.
Concentration of E-cadherin in the blood serum or urine may be determined using a specific ELISA.
Obtaining a culture of tumour cells which do not express E-cadherin on their cell membrane ;.
Thus, E-cadherin forms adherens junctions that connect the actin cytoskeletons of neighbouring cells.
This disease is associated with changes or mutations caused by a gene called E-cadherin or CDH1.
In a particular embodiment of the method, the E-cadherin ligand compound is labelled with a detectable molecule.
Detailed description Snail is a transcription factor which acts as a direct repressor of E-cadherin expression.
The epithelial cells in this tissue express E-cadherin and exhibit apical-basal polarity.
This cell population did not express the epithelial markers cytokeratin and E-cadherin.
There was also a significant decrease in expression of E-cadherin following treatment with the DE protocol.
E-cadherin The inventors have found that increasing expression of E-cadherin enhances stem cell survival.
P-cadherin expression is limited to the basal layer and E-cadherin is located throughout the epidermis.
Loss of E-cadherin expression is considered as a molecular hallmark of EMT.
Both of these proteins are transcriptional repressors of E-cadherin and their expression induces EMT.
Identified E-cadherin transcript variants arise from mutation at consensus splice sites . Vimentin.
Illustrate that AREG induces ovarian cancer cell invasión by down-regulating E-cadherin expression.
Studies in mouse embryos have shown that E-cadherin gene mutations result in pre-implantation defects.
Other tumor suppressors and related proteins These include APC and E-cadherin.
Note that the distribution of E-cadherin is non-contiguous in cells treated with the cyclic peptide.
E-cadherin is an endogenous ligand of integrin aEB7.
These results indicate that Tzv regulates E-cadherin activities through inhibition of endocytosis of E-cadherins Fig.
E-cadherin is a calcium-dependent protein responsible for cell-cell adhesion.
Increased expression of E-Cadherin.
When e-cadherin stops working, the cells become loose.
The immunophenotype pattern was considered e-cadherin positive and β-catenin positive, or negative.
