Examples of 'e-selectin' in a sentence
Meaning of "e-selectin"
e-selectin (adjective) - This term may relate to the protein selectin, specifically E-selectin, which is involved in cell adhesion processes in the body. It could indicate a characteristic or quality related to the function or properties of E-selectin
How to use "e-selectin" in a sentence
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e-selectin
E-selectin is normally absent from endothelial cells.
In the fight against inflammation, magnesium inhibits a molecule called e-selectin.
E-selectin is involved in the regulation of inflammation.
Compounds, compositions and methods using e-selectin antagonists for mobilization of hematopoietic cells.
E-selectin also interacts with other ligands on HSCs.
Thus, only one calcium binding site appears to exist in the E-Selectin lectin domain.
E-selectin is actually one of three selectins now known.
No significant changes in blood E-selectin concentrations were observed.
E-selectin inhibitors are known in the art.
There was no binding observed for either antibody to E-selectin.
E-selectin can also be administered in an aerosol or inhaled form.
The black bars show expression levels of E-selectin.
E-selectin is expressed in vascular endothelial tissue where cells have been activated.
Similar results with endothelial cell E-selectin were obtained.
E-selectin is preferably used in the practice of this invention using a series of administrations.
See also
An inhibition assay may be used to screen for antagonists of E-selectin.
E-selectin recognizes and binds to sialylated carbohydrates present on the surface proteins of certain leukocytes.
These integrins interact with E-selectin molecules found on inflamed skin.
In one preferred embodiment the protocol consists of booster intranasal administrations of E-selectin.
Soluble E-selectin was unchangeable after the procedure.
One aspect of the current invention is a method for inducing E-selectin tolerance in a host.
A saturated amount of E-selectin was used in the experiments after a serial titration.
This invention meets these needs by providing a means for inducing tolerance of E-selectin.
Binding of the conjugate to E-selectin was studied using surface plasmon resonance and immunohistochemistry.
Human aortic endothelial cells were stimulated with TNF to induce cell surface expression of E-selectin.
These results suggest that E-selectin is involved primarily in the acute inflammatory response.
The DNA and derived protein sequence of the cDNA encoding the E-selectin homologous murine sequence.
The geometric mean of the E-selectin fluorescent signal was determined from the histogram.
The researchers found that breast cancer cells express multiple proteins that may bind to E-selectin.
A recent series of publications confirmed that the E-selectin ligand also has a carbohydrate character.
Synergistic activation between steroid receptors and Rel proteins was also found with the E-selectin promoter.
E-selectin and VCAM expression were then measured.
Preferably, this protocol involves administering E-selectin every other day for ten days.
We probed the EST database in silico with the lectin domain of E-selectin.
The current aspect of the invention for inducing E-selectin tolerance has many utilities.
E-selectin expression was then measured.
Results of the delayed-type hypersensitivity assay demonstrated that intranasal instillation of human E-selectin induced tolerance.
Sequence homology between the E-selectin lectin domain and an EST.
Neutrophils and eosinophils bind to E-selectin.
This data demonstrates that the E-selectin administration protocol used induced tolerance to E-selectin.
Such antibodies recognize a common antigen determinant on E-selectin and L-selectin.
One of the reported ligands for E-selectin is the sialylated Lewis X antigen SLex.
In E-Selectin the arginine at position 97 was also important for sugar recognition.
HCELL activity can be measured for example by L-selectin or E-selectin binding activity.
E-selectin supports adhesion of neutrophils, monocytes, eosinophils, and some lymphocytes.
Suitably, the engineered NK cells exhibit a high level of E-selectin ligand expression.
Somewhat later, E-selectin binding also appears.
More preferably, it is administered at the same time as E-selectin.
Additionally, migration in an E-selectin coated flow-cell was monitored.
The co-stimulatory agent is preferably administered within 24 hours of administration of E-selectin.
