Examples of 'ectodomain' in a sentence
Meaning of "ectodomain"
ectodomain (noun): Ectodomain is a term used in biology and biochemistry to describe the extracellular portion of transmembrane proteins, often involved in cell signaling and interactions
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- The portion of a polypeptide on a cell membrane that extends beyond the membrane into the extracellular space.
How to use "ectodomain" in a sentence
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ectodomain
This event is also referred to as ectodomain shedding.
An ectodomain recognizes antigen.
The region humanized is the ectodomain.
The ectodomain of the mannose receptor has eight carbohydrate recognition domains.
The external domain of a protein is also known as an ectodomain.
The WT ectodomain sequence failed to express as a secreted protein.
There is a strong preference for certain domains to occur in the ectodomain of RTKs.
The ectodomain of SH is referred to as SHe.
A feline coronavirus spike protein is a feline coronavirus membrane protein comprising an ectodomain.
The juxtamembrane domain therefore connects the ectodomain with the transmembrane domain.
Sequester the ligand and remove it with antibody or with soluble receptor ectodomain.
The invention also provides a composition comprising MET ectodomain fragment proteins of the invention.
The ectodomain of the VSV G gene was also amplified by PCR and gel purified.
This is consistent with it being composed of TNALP ectodomain monomers.
The folding of G ectodomain was studied along two axes.
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The invention further provides an isolated protein which consists of a MET ectodomain fragment.
Alternatively, the ectodomain is chemically linked to the carrier.
In some embodiments, less than an entire ectodomain is used.
Alternatively, the ectodomain is chemically linked to the earner.
Preferably, the heterologous genome segment encodes a glycoprotein ectodomain.
Obtaining the crystallographic structure of the G ectodomain of MOKV could validate these results.
Preferably said ectodomain is presented as an oligomer, even more preferably as a pentamer.
The binding affinity of the compounds for the ectodomain of APP was determined using SPR.
The ectodomain may be presented as an oligomer, even more preferably, as a pentamer.
Generally the polynucleotides encode for all or part of the ectodomain e . g.
The ectodomain comprises the CS1-binding region and is responsible for antigen recognition.
Generally the polynucleotides of the invention encode for all or part of the ectodomain e . g.
Trastuzumab has been shown to inhibit HER2/neu ectodomain cleavage in breast cancer cells.
GP5 is a predicted three transmembrane protein with an endodomain and ectodomain.
The NRCAM ectodomain can be shed from the cell surface by metalloprotease-like activities.
In a particular embodiment, said antibody is specifically binding to the ectodomain of BACE1.
The ectodomain from the virus trimeric surface protein is heterologous with respect to the TM / CT.
In addition, this cysteine residue was deleted from the ectodomain of the M protein.
The ectodomain is composed of three SRCR domains, the intervening sequences and a stalk region.
Recombinant human and mouse TEM8 ectodomain proteins were used as the target for selection.
The composition optionally may contain HGF / SF or a fragment thereof which binds to said ectodomain.
Again, isolated syndecan ectodomain from NMuMG cells can be used for comparison . EXAMPLE III.
BACE is an aspartyl-protease that cleaves APP in its luminal domain, generating a secreted ectodomain.
The underlined AA represent the ectodomain of the RSV A small hydrophobic protein ( SHe ).
Hybridoma supernatants were first screened by ELISA on immobilized BACE ectodomain ( immunogen ).
The sequence of the gp41 ectodomain was retrieved from the SwissProt database.
Compositions In another aspect, the invention provides a MET ectodomain fragment composition.
The ectodomain includes the amino-terminal region, two leucine-rich repeats, and the intervening hydrophilic region.
The Lgr subfamily is unique in carrying a large leucine-rich ectodomain important for ligand binding.
As shown, shed HGFR ectodomain impaired Akt activation and behaved as a " decoy ".
PCR products were amplified coding different length of L1 ectodomain regions.
According to the present invention, the ectodomain comprises an anti-TOSO single-chain domain.
Furthermore a Gly - Ser linker was inserted between the POMC signal peptide and the IGS5 ectodomain.
The HGFR shed ectodomain behaves as a " decoy ".
The humanized IL-6Ra may comprise a human ectodomain.
