Examples of 'eluxadoline' in a sentence
Meaning of "eluxadoline"
Eluxadoline is a noun that refers to a medication used to treat irritable bowel syndrome with diarrhea
How to use "eluxadoline" in a sentence
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eluxadoline
It is unknown whether eluxadoline is excreted in human milk.
Truberzi contains the active substance eluxadoline.
No human data on the effect of eluxadoline on fertility are available.
Eluxadoline is also an agonist at the kappa opioid receptor κOR.
Truberzi is a medicine that contains the active substance eluxadoline.
Eluxadoline may cause constipation.
The active substance is eluxadoline.
Eluxadoline has not been specifically studied in patients who have renal impairment.
There is limited amount of data from the use of eluxadoline in pregnant women.
Eluxadoline has linear pharmacokinetics with no accumulation upon repeated twice daily dosing.
Hepatic impairment or coadministration with cysclosporine results in significant increases in plasma concentrations of eluxadoline.
Eluxadoline This medicine is subject to additional monitoring.
All patients should be instructed not to use alcohol while on treatment with eluxadoline.
IBS agents such as eluxadoline and lubiprostone to reduce symptoms.
Process for the preparation of intermediates useful in the synthesis of Eluxadoline.
See also
In animals, eluxadoline interacts with opioid receptors in the gut.
Systemic exposure to medicinal products metabolised by CYP3A4 may be decreased when coadministered with Eluxadoline.
Eluxadoline also reverses hyperalgesic responses in an animal model of acute colitis-induced visceral pain.
Examples include diphenoxylate, loperamide, and eluxadoline.
Eluxadoline is a substrate of the hepatic efflux transporter MRP2.
There is a potential for increased risk of constipation when taking eluxadoline see section 4.8.
The absorption of eluxadoline was rapid under fasting conditions, with a median Tmax value of 2 hours.
These patients are at risk for significantly increased plasma concentrations of eluxadoline see sections 4.4 and 5.2.
Eluxadoline increases the concentrations of drugs which are OATP1B1 and BCRP substrates.
Hypersensitivity to eluxadoline or to any of the excipients listed in section 6.1.
Eluxadoline should not be administered concomitantly with such medicinal products see section 4.3.
Also, co-administration of eluxadoline with rosuvastatin may increase the risk of rhabdomyolysis . [ 1 ].
Eluxadoline is a locally acting, mixed mu opioid receptor ( μOR ) agonist and delta opioid receptor.
Eluxadoline is an inhibitor of the hepatic uptake transporter OATP1B1.
Eluxadoline is a substrate of the hepatic uptake transporter OATP1B1.
Eluxadoline may increase the exposure of co-administered medicinal products metabolised by Cytrochrome CYP3A4.
