Examples of 'endosomal' in a sentence
Meaning of "endosomal"
Endosomal is an adjective used in biology to describe something related to or located in an endosome, a membrane-bound organelle
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- Of or pertaining to an endosome
How to use "endosomal" in a sentence
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endosomal
Motif and an endosomal targeting sequence.
He was among the first to characterize the endosomal system.
Alix is an endosomal pathway marker.
Fusion depends on the acidification of the endosomal compartment.
This is consistent with endosomal uptake followed by intracellular transport to lysosomes.
Another possible mechanism which can be excluded is endosomal rupture.
Various peptides also disrupt endosomal membranes in a pH dependent manner.
These effects required internalisation of the oligonucleotide and endosomal maturation.
Raising the endosomal pH with drugs such as chloroquine has demonstrated this.
Assay for assessment of endosomal transport.
Endosomal disruption factors and nuclear localizing signals have been employed in these vectors.
The particles may be formed by inward budding of the endosomal membrane.
Accumulation into endosomes and endosomal escape is monitored using high content screening.
The virus does this by fusing its membrane with the endosomal membrane.
The endosomal membrane disruptive properties is evaluated by determining the extent of lysis of erythrocytes.
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This could enhance the effectiveness of the endosomal membrane disruption agent.
This molecule increases endosomal pH through its ions transfer properties across cell membranes.
At least two pathways have been developed for disrupting the endosomal membrane.
A substance that raises the endosomal pH will prevent the appearance of the red fluorescence.
Delivery polymers provide a means of disrupting cell membranes and mediate endosomal release.
More preferably the adenoviral vector comprises an endosomal peptide loading compartment localizing peptide.
Such peptides mimic the structure of virus proteins which destabilize endosomal membranes.
Multivesicular bodies are endosomal compartments that sort ubiquitinated membrane proteins by incorporating them into vesicles.
Materials bound to these receptors are delivered to endosomal compartments inside the cell.
The endosomal compartment then recycles the Fc to the cell surface.
The toxin is then translocated through the endosomal membrane into the cytosol.
In certain embodiments, the endosomolytic ligand assumes its active conformation at endosomal pH.
The virus is preferably a virus that uses the late endosomal pathway or lysosomal pathway.
In another aspect, the endosomal targeting domain comprises a transmembrane sequence.
The peptides of the methods of the invention optionally comprise an endosomal targeting sequence.
The nuclear entry and efficient endosomal escape of HPNPs result in high gene transfection efficiency.
Such destabilizing structures should be able to disturb or destabilize the endosomal membrane systems.
Accumulation of the TSI into endosomes and endosomal escape is monitored by high content screening.
These melanogenic enzymes travel via the secretory pathway and early endosomal intermediates.
DNase II in the endosomal or lysosomal compartment.
Molecules that enable passage through the cell membrane or the membrane of endosomal vesicles.
This protein may be involved in endosomal trafficking, microtubule dynamics, or both functions.
These amphipathic helices can then penetrate and cause disruption of the endosomal membrane.
In addition, the particles demonstrated endosomal escape, indicating efficient intracellular targeting.
Polyethylenimine which facilitates gene expression without additional treatments probably disrupts endosomal function itself.
These compounds are internalised by endosomal route and are localised after 16 hours in the lysosomes.
SFV induces small invaginations called spherules on plasma membrane and on endosomal membranes.
At higher concentrations than those required to inhibit endosomal acidification, nonspecific inhibitory effects were observed.
The invariant chain folds and directs the MHCII molecules to the endosomal pathway.
Recently, two new types of CPPs with improved endosomal escape efficiencies have been discovered.
Form B of HA is required for fusión of the virus envelope with the endosomal membrane.
For liposomal vectors, the endosomal membrane barrier continues to limit the efficiency of gene delivery.
Disassembled adenovirus escapes to the cytosol by release of the endosomal contents into the cytoplasm.
Payloads are released from the endosomal compartment within 24 hours into the cytoplasm and nuclear compartments.
Molecular mechanism of cystic fibrosis mutation associated with endosomal recycling defect of CFTR.
