Examples of 'enkephalinase' in a sentence
Meaning of "enkephalinase"
Enkephalinase is an enzyme that breaks down enkephalins, which are pentapeptides involved in regulating various physiological functions
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- Any of a class of enzymes that degrade endogenous enkephalin opioid peptides.
How to use "enkephalinase" in a sentence
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enkephalinase
Rat kidney enkephalinase was purified to apparent homogeneity.
New form of administration of enkephalinase inhibitor.
Enkephalinase is partially purified from rat kidney.
Determination of the enkephalinase inhibiting effect.
Enkephalinase has been implicated in the mechanism.
Nucleotide and amino acid sequence of human enkephalinase.
Enkephalinase inhibiting activity of deuteroaldehydes and derivatives thereof.
These compounds are useful as inhibitors of enkephalinase.
Inhibition of enkephalinase would also potentiate endogenous levels of bradykinin.
The compounds are disclosed as having enkephalinase inhibiting activity.
The enkephalinase activity was determined from a renal membrane fraction of a rat.
It also enables the preparation of novel forms of enkephalinase.
In vitro inhibition of enkephalinase activities.
Enkephalinase has been found to be bound to the cell membrane of human neutrophils.
Nucleotide and amino acid sequence of rat enkephalinase.
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It is indeed known that enkephalinase is a peptidase which degrades in particular enkephalins.
This in vitro translated material is assayed for enkephalinase activity.
The large size of enkephalinase could account for this difficulty.
Examples of peptides would be somatostatin analogues and enkephalinase inhibitors.
The activity of enkephalinase was determined starting with a piece of renal membrane of a rat.
Partial cDNA clones encoding rat enkephalinase were obtained.
Inhibition of enkephalinase would therefore be useful in a patient suffering from acute or chronic pain.
An assay was used to test the effects of enkephalinase on neutrophil chemotaxis.
Enkephalinase activity was measured as described by Llorens et al.
The isolation and identification of the enkephalinase gene was extremely difficult.
Compositions and methods for the synthesis and assay of enkephalinase.
The complete reading frame for enkephalinase was obtained from two overlapping clones.
Extraction and purification of the human salivary compounds potentially regulators of enkephalinase activity.
Inhibition of Enkephalinase Enkephalinase activity was determined in a striatum membrane fraction of rats.
The invention further provides an improved substrate for the assay of enkephalinase activity.
Thus, neutrophil enkephalinase modulates chemotactic activity.
The combinations of the invention greatly optimize the administration of enkephalinase inhibitors administered alone.
Acetorphan is an enkephalinase inhibitor that blocks epithelial cyclic AMP-mediated secretion.
The combinations of the invention significantly improve the action of enkephalinase inhibitors administered alone.
Enkephalinase and its recombinant expression product was obtained according to the following protocol,.
The tryptophan and tyrosine containing substrates can be used for continuous recording of enkephalinase activity.
The derivatives of this invention are inhibitors of enkephalinase which is an enkephalin-degrading enzyme.
SDS Polyacrylamide electrophoresis gel of purified rat kidney enkephalinase.
Further substituted amino acid derivatives are known as enkephalinase inhibitors, analgesics and hypotensives.
A pharmaceutical composition according to claim 8 for inhibiting enkephalinase.
Antidiarrheal ; enkephalinase inhibitor, reducing the amount of water and electrolytes into the intestine.
Sequence operably linked to the DNA encoding enkephalinase.
Membrane bound enkephalinase from neutrophils cleaves the chemotactic peptide fMet-Leu-Phe.
This expression vector encodes cytoplasmic domain-deleted enkephalinase.
Cytoplasmic domain-deleted enkephalinase is recovered from the transformant culture of pCIS-Enkinsol transformants.
On this basis, there has recently been active research and development on enkephalinase inhibitors.
Cytoplasmic and transmembrane domain-deleted enkephalinase is recovered from the culture of pCIS-Enksol transformants.
Figure 1 Nucleotide and amino acid sequence of human enkephalinase.
Purified enkephalinase was digested with Lysine C-proteinase.
The N-terminal amino acid sequence of enkephalinase was determined.
