Examples of 'ephrin' in a sentence
Meaning of "ephrin"
ephrin (noun): A type of protein involved in cell signaling, used in a scientific or biological context. ~ Ephrin is a protein that plays a role in cell signaling and is often studied in the field of biology
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- Any of a class of proteins that are involved in cell signalling
How to use "ephrin" in a sentence
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ephrin
Functions of ephrin proteins in malignant lymphocytes.
Cell based studies were performed with recombinant ephrin treatments and ephrin knockdowns.
We now know that ephrins and ephrin receptors play an important role in.
A recent review concerning Eph receptors and ephrin signaling ref.
Eph RTKs and their ephrin ligands play important roles in embryonic vascular development.
Then, we put explants next to patterned gradients of ephrin.
Ephrin binding induces Eph receptor oligomerization causing phosphorylation of juxtamembrane residues of Ephs.
In one instance, said antigen binding domain binds an ephrin receptor or a claudin.
When ephrin is freed from the opposing cell, the entire ephrin/eph complex is endocytosed.
EphB3 is a receptor in the ephrin receptor tyrosine kinase family.
Ephrin receptors ( Ephs ) are a group of receptors that are activated in response to binding ephrin.
A preferred member of the eph family is ephrin B4.
The binding of ephrin ligands to Eph receptors is dependent on cell-cell interactions.
Western blot was performed with monoclonal antibody to ephrin B2 generated in-house.
EphA3 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family.
See also
One polypeptide therapeutic agent of the invention is a soluble polypeptide of Ephrin B2 or EphB4.
Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase ( RTK ) family.
EphA3 is a member of the Eph receptor family which binds Ephrin ligands.
As an indicator for Ephrin activation, the consortium used the phosphorylation of tyrosine kinase receptors.
The polypeptide agent employed may inhibit clustering or phosphorylation of Ephrin B2 or EphB4.
Ephrin B / EphB signaling is also involved in synaptic stabilization through different mechanisms.
Examples of the modified polypeptide include PEGylated soluble Ephrin B2 and PEGylated soluble EphB4.
A polypeptide of the Ephrin type A9 receptor family selected from one of the groups consisting of,.
Dark blue color in the ISH indicates positive reaction for ephrin B2.
Inhibition of ephrin B2 by neutralizing antibodies.
Furthermore, in silico analyses points to structural complementarity between EPO and Ephrin molecules, particularly Ephrin A1.
Ephrin B is an “ axon guide, ” one of a surprisingly small number of such proteins.
Presently there are 14 Eph receptors and 9 ephrin ligands known in humans.
Neither EphB4 nor ephrin B2 sense probes hybridized to the sections, proving specificity of the signals.
Therefore, in second part of my study, I investigated the role of ephrin B2 in fibrosis.
Figure 34 shows expression of ephrin B2 and EphB4 by in situ hybridization in mesothelioma cells.
The soluble EphB4 polypeptide may inhibit clustering of or phosphorylation of Ephrin B2 or EphB4.
Astrocytes and their processes express ephrin A3, whereas the EphA4 receptor is enriched in hippocampal neurons.
Figure 14 is a schematic representation of human Ephrin B2 constructs.
The soluble EphrinB2 polypeptide may inhibit the interaction between Ephrin B2 and EphB4.
Culturing the pancreatic endoderm cells with an Ephrin ligand enhances expression of insulin and NKX6.1.
Use according to any one of claims 15 to 20 wherein the agonist binds an ephrin ligand.
The use according to Claim 9, wherein the ephrin expressed by said another cell is ephrin A5.
Ephrin B2 was also detected in KS using EphB4-AP fusión protein ( bottom left ).
These results confirm co-expression of EphB4 and Ephrin B2 in mesothelioma cell lines.
In this embodiment, EphA2 may or may not be crosslinked to its ligand, Ephrin A1.
OMgp - Oligodendrocyte myelin glycoprotein Ephrin B3 functions through the EphA4 receptor and inhibits remyelination.
KS-SLK cells were transfected with various siRNA to ephrin B2 and controls.
Binding of Ephrin B2-AP fusión to EphB4-derived recombinant proteins immobilized on Ni-NTA-agarose beads.
The in vitro culture of claim 6, wherein the Ephrin ligand is Ephrin A4.
Specific examples of Ephrin B2 soluble polypeptides are provided in Figures 3 and 14.
Use according to claim 24 wherein the ephrin ligand is Ephrin-B2.
Figure 45 shows that Ephrin B2, but not EphB4 is expressed in KS biopsy tissue.
Figure 35 shows cellular expression of EphB4 and ephrin B2 in mesothelioma cultures.
Representative human Ephrin B2 constructs and human EphB4 constructs are shown Figures 14 and 15.
