Examples of 'epimerization' in a sentence
Meaning of "epimerization"
epimerization (noun): A chemical process where epimers, which are stereoisomers that differ in the configuration of a single stereogenic center, interconvert into each other.
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- The process of forming an epimer by changing one asymmetric centre in a compound that has more than one
How to use "epimerization" in a sentence
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epimerization
The success of this epimerization step is surprising.
No epimerization was observed and only isosorbide was recovered.
General procedure for epimerization of rapamycin.
Epimerization of this stereocenter had been accomplished in a following step.
A short note on the epimerization of aldoses.
Variant b is a substitution reaction under simultaneous or concomittant epimerization.
Processes for lactulose epimerization by magnesium compounds are also known.
The metal salt can act as a catalyst in epimerization.
Epimerization is a known degradation path.
Process variant a is a substitution reaction under simultaneous epimerization.
Another isomer is obtained by epimerization of one center on the cyclobutane ring.
Reagents and solvent are not necessary to promote epimerization.
The epimerization can be made to occur thermally and therefore requires a sufficiently high temperature.
One of them is oxidative degradation and another one is epimerization.
Epimerization occurring on the wrong position would complete destroy the ability to recycle the material.
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Serine is well known for its sensitivity towards epimerization.
An epimerization limited to one third of the uronic acids had been formerly described M.
Carbohydrate acids may also be obtained by epimerization of other carbohydrate acids.
Only well defined operating conditions permit obtaining an interesting percentage of epimerization.
Epimerization means interconversion of one enantiomer into another proceeding through a common intermediate B see scheme below.
It was found that either coupling protocol or the coupling reagents influence the epimerization rate.
NMR investigations indicated fast epimerization of the metal center on the NMR time scale.
According to a preferred embodiment the intermediate depolymerization is carried out after the epimerization step b.
At lower pH, epimerization emerges as the most predominant degradation pathway.
Under these conditions, no significant epimerization was observed.
The degree of epimerization is dependent upon pH, and is greatest at a pH of approximately 3.
Usually, picropodophyllin is obtained from its stereoisomer podophyllotoxin by epimerization.
This compound was obtained by epimerization of its trans isomer prepared in example 1.
Preparation of alkylsubstituted indoloquinolizidine lactams and their acid-catalysed epimerization.
Tetracyclines undergo reversible epimerization to the less active epi-tetracycline.
The process of claim 10 wherein the carbohydrate for reducing epimerization is lactose.
Scheme 2 illustrates the epimerization of a stereocenter followed by hydrolysis of an ester to an acid.
In large part, this degradation is due to the epimerization of these materials.
We did not observe any epimerization of the substrate or product acid during work-up.
Since the monomeric components of dermatan sulfate are saccharides, they are susceptible to epimerization.
In peptide chemistry, racemization also means epimerization at one of several chirality centers.
The epimerization reaction has been observed in alkaline, neutral, and strongly acidic media.
In the case of the tyrosine-bound to the solid-support no epimerization was observed.
Epimerization vía pyramidal inversion represents an ideal reaction in terms of atom efficiency and work-up.
The method according to claim 8 wherein the epimerization is carried out by the steps of,.
More preferredly, the hydrolysis reaction is completed using saponification conditions to avoid epimerization.
This prevents the epimerization of the sugars, which would otherwise occur in an alkaline medium.
The configuration at the α-position is less predictable, especially in cases when epimerization can occur.
Under the reductive amination conditions, epimerization occurred to provide only the trans isomer.
In some embodiments, the compositions have improved stability against both oxidative degradation and epimerization.
Epimerization at the amino acid alpha-carbon is a known problem that plagues polypeptide synthesis and stability.
For instance, synthetic routes involving epimerization of podophyllotoxin into picropodophyllin are described in Angew.
By epimerization reactions, by application or adaptation of the methods described in Adv . Carbohydr.
HYDZ has a chiral center adjacent to the carbonyl carbon, which is particularly susceptible to epimerization.
After reaction epimerization was observed obtaining a mixture of diastereomers which were separated by Method 3C.
