Examples of 'episomal' in a sentence
Meaning of "episomal"
Episomal is an adjective used in genetics to describe genetic material that exists separately from the chromosome
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- Pertaining to an episome or DNA fragments not contained within a chromosome
How to use "episomal" in a sentence
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episomal
It can be present in episomal or chromosomal form.
Episomal vectors are known in the art.
The vector may be an episomal vector or an integrating vector.
Alternatively it may be present in episomal form.
A preferred episomal vector is the adenovirus.
Vectors which are maintained autonomously are referred to as episomal vectors.
The vector may be an episomal vector or a vector that is maintained extrachromosomally.
Cellular chromatin includes both chromosomal and episomal chromatin.
Cells allowing episomal amplification of nucleic acids greatly reduce the rate of dilution.
The vector may be episomal.
The cassettes can remain episomal or integrate into the host cell genome.
The construct may be integrated into the chromosome or episomal.
This vector may alternatively be either an episomal or an integrating vector.
The nucleic acid encoding the exogenous polypeptide can be episomal.
Removal of selective pressure did not affect the episomal status of the derived molecules.
See also
The genetic construct can be integrated into the cell or remain episomal.
These should allow high copy number episomal replication and may be more effective.
Vectors that are maintained autonomously in eukaryotic cells are referred to as episomal vectors.
The present disclosure provides an extended episomal maintenance system with heterologous replication origin.
The episomal expression vector comprises a promoter that controls the transcription of reprogramming genes.
Vectors having a bacterial origin of replication and episomal mammalian vectors.
Nucleoside prodrugs affect the episomal proliferation of papilloma virus thereby inducing regression of the warts.
For example the vectors may be plasmids which can be episomal or integrating.
The episomal persistence of the PyV origin containing plasmids was analyzed by Southern blotting.
This further vector may be integrative or episomal when transformed into the host organism.
These findings confirmed that gene expression disappears earlier in plasmid vectors than in episomal vectors.
The expression cassette may be contained in an episomal expression vector within the producer cell.
Only episomal replicating DNA vectors showed positive results.
This could be achieved using host cells carrying episomal copies of the baculoviral genome.
Episomal DNA is also contemplated.
Such expression vectors may remain episomal or may integrate into the host cell genome.
Said heterologous DNA may be contained in or may be an episomal element.
The cccDNA of viruses is also known as episomal DNA or occasionally as a minichromosome.
Field of the Invention The invention relates in general to episomal vectors.
We conclude from this result that the episomal Ga subunits constructs are unstable.
Episomal and chromosomal DNA was extracted at time points indicated in Results section.
This amplicon system or similar amplicon components permit high copy episomal replication in the cells.
Analysis of the episomal state of DNA plus FISH inspection was performed.
The transforming DNA may be maintained on an episomal element such as a plasmid.
Levels of the episomal DNA were determined in relation to the integrated HBV DNA.
The term includes expression systems that remain episomal or integrate into the host cell genome.
Suitable episomal nucleic acid constructs may e . g.
The selection marker gene can be used on an episomal DNA vector.
Episomal replication is also possible in mammalian cells e . g.
There can exist also extrachromosomal or episomal DNA as plasmids in the cell.
Alternatively, the nucleic acid can remain episomal.
In addition, episomal vectors may be employed.
TRECs do not replicate because they are episomal DNA circles.
In one embodiemnt, an episomal expression vector comprises a gene of interest.
In this disclosure, the vector can be episomal.
