Examples of 'evolocumab' in a sentence
Meaning of "evolocumab"
Evolocumab (noun): A type of medication used to lower cholesterol levels
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- A human monoclonal antibody designed for the treatment of hyperlipidemia.
How to use "evolocumab" in a sentence
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evolocumab
It is unknown whether evolocumab is excreted in human milk.
Evolocumab had no observed effect on cardiovascular mortality.
Repatha contains the active substance evolocumab.
No data on the effect of evolocumab on human fertility are available.
The active substance is evolocumab.
The effect of evolocumab on cardiovascular morbidity and mortality has not yet been determined.
The mutagenic potential of evolocumab has not been evaluated.
Evolocumab is generally well-tolerated with an established safety profile.
One practical consideration regarding evolocumab is its cost.
Evolocumab ( trade name Repatha ) is a monoclonal antibody designed for the treatment of hyperlipidemia.
The pharmacokinetic interaction between statins and evolocumab was evaluated in the Repatha clinical trials.
So far, clinical studies of alirocumab suggest it is similar in effectiveness to evolocumab.
The CHMP recommended granting evolocumab marketing authorization for,.
Clinical efficacy and safety of achieving very low LDL-cholesterol concentrations with evolocumab.
An approximately 20 % increase in the clearance of evolocumab was observed in patients co - administered statins.
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There are currently two PCSK9 inhibitors on the market, alirocumab and evolocumab.
An approximately 20 % increase in the clearance of evolocumab was observed in patients co-administered statins.
What Repatha contains - The active substance is evolocumab.
Adding the ' investigational biologic ' evolocumab to statin therapy works better, study says.
Evolocumab has been designed to attach to a protein called ‘ PCSK9.
Less impact from body weight was seen with repeated subcutaneous evolocumab 420 mg monthly doses.
Evolocumab is a fully human monoclonal antibody that inhibits proprotein convertase subtilisin / kexin type 9 PCSK9.
LDL cholesterol was reduced by up to 56 percent in patients using evolocumab.
The exposure to evolocumab was found to be approximately 40-50 % lower compared to healthy subjects.
There is two PCSK9 inhibitors on the market, alirocumab and evolocumab.
Evolocumab and arilocumab ( PCSK9 inhibitors ), preliminary results.
Repatha 140 mg solution for injection evolocumab.
Evolocumab is used to help lower " bad " cholesterol ( LDL ) in the blood.
Repatha 420 mg solution for injection in cartridge evolocumab.
A clinical study using Amgen 's evolocumab included 4,465 patients with varying degrees of cardiovascular risk.
Each SureClick pre-filled pen contains 140 mg of evolocumab in 1 mL of solution.
Repatha 140 mg solution for injection in pre-filled pen evolocumab.
Amgen submitted a biologics license application ( BLA ) for evolocumab to the FDA in August 2014.
Repatha 140 mg solution for injection in pre-filled syringe evolocumab.
