Examples of 'factor viia' in a sentence

Meaning of "factor viia"

Factor VIIa: This phrase refers to an activated form of Factor VII, a protein involved in blood clotting

How to use "factor viia" in a sentence

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factor viia
Tissue factor binds to circulating factor VIIa.
Certain inhibitors of factor VIIa have already been described.
A factor VIIa molecule was produced by procedures outlined above.
Stabilised solid compositions of factor VIIa polypeptides.
The factor VIIa protein can be recombinantly produced or modified as well.
It is treated with recombinant factor VIIa NovoSeven or AryoSeven.
The mutants are active in the presence of factor VIIa.
The compositions contain factor VIIa and fibrinogen.
The mammalian host cell includes modified factor VIIa.
Administration of recombinant factor VIIa is an increasingly used therapeutic alternative.
Two of these patients had also received recombinant factor VIIa.
A second dose of recombinant factor VIIa resulted in complete cessation of bleeding.
Work has accordingly been performed to identify and optimize factor VIIa inhibitors.
Recombinant factor VIIa is used to control bleeding episodes in hemophilia patients with inhibitors.
Coagulation factor VIIa.

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The functionality of factor VIIa or a functional equivalent may be tested by administering a prothrombin assay.
It is a necessary aspect of the invention that factor VIIa is in an activated form.
Redosing of recombinant factor VIIa could be considered and titrated depending on improvement of bleeding.
The active substance is recombinant coagulation factor VIIa activated eptacog alfa.
Factor VIIa is a plasma serine protease involved in the initiation of the coagulation cascade.
The assay is also suitable for selecting suitable factor VIIa variants.
A recombinant form of factor VIIa will still retain the functional characteristics of native factor VIIa.
The mechanism of action includes the binding of factor VIIa to exposed tissue factor.
Eleven loop regions were identified in the sequence of the catalytic domain of factor VIIa.
Factor Viia was recovered in the final eluate.
Antibodies in the second specificity class are developed by immunizing mice with recombinant factor VIIa.
Exogenous Factor VIIa could also be administered to the patient.
A complete necropsy was performed on the animal receiving truncated tissue factor and factor VIIa.
The Factor VIIa may be from any suitable source.
In a further embodiment the factor VIIa is a Factor VIIa variant.
The clotting factor may be factor VII or factor VIIa.
In a further embodiment the factor VIIa is recombinant human Factor VIIa.
Doses can be timed to provide prolong elevation in Factor VIIa levels.
The modulator of Factor VIIa may be administered in the form of a solution.
Pharmaceutical composition comprising a factor VIIa and a factor XIII.
Factor VIIa or FVIIa variants are incubated with FX in the presence of phospholipid vesicles.
The following method can be used to assay Factor VIIa bioactivity.
Factor VIIa complexed with tissue factor can autoactivate inactive factor VII.
One set of cells did not have Factor VIIa added as a negative control.
TF is the cell surface receptor for the serine protease factor VIIa.
Monoclonals that react with factor VIIa but not factor VII are selected.
A pharmaceutical composition for intravenous administration comprising a factor VIIa and a factor XIII.
The appropriate doses of Factor VIIa can best be determined in light of this information.
The present invention provides a composition comprising a combination of a factor VIIa and a factor XIII.
The ability of factor VIIa to activate factor X on activated platelet surfaces also was determined.
Several clinical trials have demonstrated the efficacy of recombinant Factor VIIa to control bleeds.
Recombinant factor Viia should not be used except when all other methods have failed.
Primary screening identified hybridoma antibodies that reacted with factor VII or factor VIIa antigen.
Serial dilutions from each stock of Factor VIIa mutant were all prepared in plasma.
Factor VIIa induces the expression of CTGF.

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