Examples of 'fetal fraction' in a sentence
Meaning of "fetal fraction"
Fetal fraction: Refers to the percentage of cell-free fetal DNA in the bloodstream of a pregnant woman
How to use "fetal fraction" in a sentence
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fetal fraction
Fetal fraction affects performance of the test.
Simultaneous determination of aneuploidy and fetal fraction.
Often a fetal fraction is provided as a percent.
Such information may be used to determine fetal fraction.
Fetal fraction information can be used in conjunction with sequencing information.
Polymorphic ligation assays were used to ascertain fetal fraction.
In some cases a mean value of a fetal fraction determination is a weighted mean.
This case contains no information about the fetal fraction.
Fetal fraction estimate is twice the slope of the regression like.
Analysis of sequencing data for the determination of fetal fraction.
In some cases a mean value of a fetal fraction determination is an unweighted mean.
In some cases determining fetal ploidy comprises determining a fetal fraction.
A closed form solution for fetal fraction is chosen to be the real solution of.
A method in which fetal gender may be determined can also comprise determining fetal fraction.
The fetal fraction determined as described herein may be used for various applications.
See also
For various heterozygosity cases the equation above can be solved for fetal fraction.
Knowledge of a fetal fraction in a sample can assist in identifying such disorders in a prenatal context.
Also provided is a method of any of the above embodiments further comprising determining fetal fraction.
Determining said fetal fraction comprises,.
As explained, polymorphisms may be used to assess the fetal fraction.
The fetal fraction can not be derived for polymorphisms falling into case 4.
Therefore, the present method can be used to predict fetal fraction.
In some cases, a determination of a fetal fraction comprises determining a fetal and / or maternal microploidy.
In some embodiments, the method further comprises estimating the fetal fraction.
Fetal fraction variability is defined as the relative standard-error of the measured fetal fraction.
Informative polymorphic sites are identified, and the fetal fraction is calculated as described.
Hence we determine fetal fraction F by solving for the following system of factorial moment relations,.
It may also be used to preferentially amplify short fragments, thereby enriching fetal fraction.
However, for a given test, the fetal fraction may only be calculated successfully once.
Example 3 Analysis of sequencing data for the determination of aneuploidy and fetal fraction.
Polymorphisms that arc designated for use in determining fetal fraction are polymorphisms that are pre-known.
For fetal fraction f to obtain the solution, EPMATHMARKEREP FIG.
The FORTE algorithm explicitly accounts for fetal fraction in calculating trisomy risk . ”.
The method according to any one of claims 1-7 further comprising determination of fetal fraction.
In some cases a measurement of fetal fraction ( F ) is determined.
No fetal fraction ( f ) estimate.
In certain cases of the method described here, fetal fraction F is fixed.
For example, a fetal fraction can be divided by 100 thereby providing a percent value.
Figure 30E, Generated plot when three chromosomes are present and the fetal fraction is 27 %.
In this case, for small fetal fraction ( / ), the observed allele frequencies will be markedly different.
Fetal fraction f estimated as 2A/D.
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