Examples of 'first-pass' in a sentence
Meaning of "first-pass"
first-pass (noun): A first-pass refers to an initial attempt or assessment, often used in the context of a first draft, examination, or evaluation
How to use "first-pass" in a sentence
Basic
Advanced
first-pass
The first-pass metabolism is believed to be negligible.
Budesonide has a high first-pass metabolism.
High first-pass yields with major reductions in defects.
Carvedilol exhibits stereoselective first-pass metabolism.
Diclofenac undergoes first-pass metabolism and is extensively metabolised.
The substance is subject to extensive first-pass metabolism.
This is called the first-pass effect or presystemic metabolism.
The substance undergoes extensive first-pass metabolism.
Digestion and first-pass metabolism do not happen in cell cultures.
There is no clear evidence of any first-pass metabolism.
Avoiding first-pass metabolism allows more of the drug to be available for treatment.
It undergoes no measurable first-pass effect in the liver.
Part of the first-pass metabolism of ethinyl estradiol is believed to occur in gastrointestinal mucosa.
This phenomenon is known as the first-pass effect.
Avoidance of the first-pass inactivation by liver.
See also
Focus on quick feedback instead of first-pass success.
This enantioselectivity in first-pass metabolism has great clinical significance.
This is likely due to the bypassing of first-pass metabolism.
Pentobarbital undergoes first-pass metabolism in the liver and possibly the intestines.
It is known that silibinin shows a pronounced first-pass effect.
It also avoids the first-pass effect in the liver.
Sibutramine is well absorbed and undergoes extensive first-pass metabolism.
This is likely because of extensive first-pass metabolism by the enzyme monoamine oxidase.
Simvastatin is well absorbed and undergoes extensive hepatic first-pass extraction.
Sublingual delivery also avoids first-pass metabolism of the active agent.
These alternative formulations maximize bioavailability and reduce first-pass metabolism.
It will also affect your first-pass transfer efficiency.
Absorption and bioavailability are decreased by transporter effects and substantial first-pass metabolism.
Clarithromycin has a fairly rapid first-pass metabolism in the liver.
First-pass images were analyzed independently by two nuclear medicine physicians, using two regions of interest.
Transdermal administration avoids first-pass hepatic metabolism.
Administered by sublingual SL or transdermal route, it exceeds the hepatic first-pass.
There is no evidence of a hepatic first-pass effect for etoposide.
The large initial uptake in the lungs after intravenous administration seems to be a first-pass effect.
This is probably due to a decrease of the first-pass hepatic metabolism in the elderly.
Especially the latter two enzymes contribute significantly to the first-pass effect.
Norgestimate is extensively metabolized by first-pass mechanisms in the gastrointestinal tract and / or liver.
These pharmaceuticals are well absorbed but have extensive first-pass sulphation.
Efficiency can be described as the first-pass retention figure for saleable paper on a paper machine.
Buspirone is rapidly absorbed in man and undergoes extensive first-pass metabolism.
Naloxone undergoes extensive first-pass hepatic metabolism that results in reduction its systemic concentration.
Parenteral administration enables this hepatic first-pass effect to be avoided.
First-pass metabolism through the lungs is substantial leading to low systemic plasma concentrations of PGE1.
This route of administeration avoids first-pass metabolism problems.
About DOP first-pass filtration efficiency.
Carvedilol is metabolised by the liver and undergoes extensive first-pass metabolism.
Nicotinic acid undergoes extensive first-pass metabolism through two pathways that are dose and dose-rate dependent.
A large number of drugs show low bioavailabilities owing to extensive first-pass metabolism.
As a first-pass model, two dimensions are enough.
These are mainly for drugs without much first-pass liver metabolism.
