Examples of 'folate receptor' in a sentence
Meaning of "folate receptor"
Folate Receptor: A protein located on the surface of cells that has a high affinity for folate, a B vitamin essential for various biological processes
How to use "folate receptor" in a sentence
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folate receptor
It is comprised of a mixture of five folate receptor alpha peptides.
A folate receptor based selection system has several advantages.
Both of them have higher folate receptor expression on cell surface.
The folate receptor protein was purified from the supernatant as follows.
Quantitative expression means determining a level of expression of folate receptor alpha.
Detection of folate receptor alpha in tissue samples can be qualitative or quantitative or both.
The binding site for the ligand is the folate receptor.
The membrane bound folate receptor can be derived from any species as is outlined above.
It has also been shown that activated monocytes overexpress the folate receptor.
The copy numbers of the mutated folate receptor alpha gene showed a comparable trend.
This applies to the mutated as well as the wild type folate receptor.
Folate receptor alpha is naturally anchored to the cell membrane by a GPI anchor.
Western blot analyses were also performed using purified folate receptor preparations.
Folate receptor 1 antibodies and immunoconjugates and uses thereof.
Activated macrophages often overexpress cell surface proteins such as the folate receptor.
See also
Alternatively, folate receptor blinding ligands unrelated to folate can be used.
Also encompassed by said term variant are fusion proteins comprising a respective folate receptor.
Alternatively, folate receptor binding ligands unrelated to folate can be used.
Qualitative detection means detecting the presence or absence of folate receptor alpha expression.
In another example, the folate receptor is overexpressed in many cancer cells.
Vintafolide is a small molecule drug conjugate consisting of a small molecule targeting the folate receptor.
Thus, the use of the folate receptor has several important advantages.
Fluorescence shift was registered only with cells expressing the human alpha folate receptor.
The folate receptor is a human folate receptor or a functional variant thereof, and / or.
Any suitable leader sequence can be used which ensures functional expression of the folate receptor.
According to one embodiment, a human folate receptor alpha is used as selectable marker.
A GPI anchor is preferred as it corresponds to the natural setting of a folate receptor.
According to one embodiment, the folate receptor is a functional membrane-bound folate receptor.
The eukaryotic cell may express endogenously DHFR and a folate receptor.
Comparing the amount of folate receptor alpha ( FRa ) present in the sample to either.
However, folic acid can be processed by the folate receptor.
According to one embodiment, the mutated folate receptor shows a reduced binding to folic acid.
Also encompassed are fusión proteins, comprising a respective mutated folate receptor sequence.
Folate receptor alpha is the antigen to which an anti-folate receptor-alpha antibody specifically binds.
Diagnostic assays and kits for detection of folate receptor 1.
In this embodiment, the folate receptor comprises a membrane anchor at its C-terminus.
Delivery of macromolecules into living cells, a method that exploits folate receptor endocytosis.
Folate Receptor Assay All sample preparation procedures used for the FR assay were performed at 4°C.
Selection system for eukaryotic cell culture based on a membrane-bound folate receptor gene.
The compound of 1 wherein V is folate, or a folate receptor binding analog of derivative thereof.
In another embodiment of the present invention, nucleic acid is delivered through folate receptor means.
In particular, a combined selection against the folate receptor and DHFR as selectable markers is beneficial.
Which is over-expressed in epithelial ovarian cancer . We target a folate receptor.
Ovarian cancer has one of the highest rates of folate receptor expression at about 85 percent.
In fact, it is estimated that 95 % of all ovarian carcinomas overexpress the folate receptor.
These important advantages make the A49L mutated folate receptor particularly suitable as selectable marker.
The folate receptor will allow the drug-chain-ball complex to enter tumour cells.
The protein encoded by this gene is a member of the folate receptor ( FOLR ) family.
Furthermore, a folate receptor as used herein is membrane-bound.
T1 is an integrin targeting component while T2 is a folate receptor targeting component.
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Examples of using Folate
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Folate deficiency is also suggested as possible mechanism
The symptoms of folate deficiency are often subtle
Folate is often confused with folic acid
Examples of using Receptor
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Receptor is not sensitive to the type of change
Is that why that receptor network existed
This receptor can exist in three conformations
