Examples of 'fosaprepitant' in a sentence
Meaning of "fosaprepitant"
Fosaprepitant is a noun that refers to a medication or a chemical compound
Show more definitions
- A prodrug of aprepitant, administered intravenously as an antiemetic.
How to use "fosaprepitant" in a sentence
Basic
Advanced
fosaprepitant
The pharmacological effect of fosaprepitant is attributed to aprepitant.
Examples of antiemetic compounds include at least fosaprepitant.
When administered intravenously fosaprepitant is rapidly converted to aprepitant.
Fosaprepitant pharmacokinetics has not been evaluated in special populations.
It contains the active substance fosaprepitant.
Effect of fosaprepitant on the pharmacokinetics of other active substances.
A preferred pharmaceutically acceptable salt is the fosaprepitant dimeglumine.
Recovering the fosaprepitant dimeglumine with desired purity by recrystallization.
The active substance is fosaprepitant.
For fosaprepitant and aprepitant no clinical data on exposed pregnancies are available.
Aprepitant after fosaprepitant administration.
Hence it is essential to provide a stable amorphous form of fosaprepitant dimeglumine.
Also polymorphs of fosaprepitant neutral form have not been reported in the literature.
Recovering the precipitated dibenzyl ester fosaprepitant solid and drying.
Fosaprepitant was rapidly converted to aprepitant in in vitro incubations with liver preparations from humans.
See also
There is a need for a reproducible process for the preparation of fosaprepitant dimeglumine.
Ivemend contains a substance called fosaprepitant which is converted in the body into aprepitant.
The fosaprepitant dimeglumine intermediate of the present invention is a stable dibenzyl ester fosaprepitant.
The present invention provides that the dibenzyl ester fosaprepitant is crystalline.
Pharmacokinetics in special populations Fosaprepitant pharmacokinetics has not been evaluated in special populations.
The application relates to a process for the preparation of a stable amorphous fosaprepitant dimeglumine.
The invention provides the use of dibenzyl ester fosaprepitant in the preparation of fosaprepitant dimeglumine.
The relationship between concentration and effect has not been evaluated after administration of fosaprepitant.
Relationship between concentration and effect Fosaprepitant is a prodrug of aprepitant.
Fosaprepitant dimeglumine is an antiemetic drug, administered intravenously.
The present invention provides a novel process for reducing palladium content in fosaprepitant dimeglumine.
IVEMEND contains the active substance fosaprepitant which is converted to aprepitant in your body.
Please refer to the Summary of Product Characteristics for fosaprepitant.
Providing a solution of fosaprepitant dimeglumine in a solvent ;.
Tabulated list of adverse reactions - fosaprepitant.
Plasma concentrations of fosaprepitant are below quantifiable levels within 30 minutes of the completion of infusion.
Concomitant administration of fosaprepitant with St.
The fosaprepitant dimeglumine can be recovered by re-crystallization techniques known in the art, preferably filtration.
Providing a solution of dibenzyl fosaprepitant in a solvent ;.
In a fourth embodiment, the present invention provides a crystalline form of a dibenzyl ester fosaprepitant.
Providing a solution of dibenzyl ester fosaprepitant in a solvent or mixture of solvents ;.
In a fourteenth embodiment, the application relates to a neutral form of fosaprepitant.
A process for reducing palladium content in fosaprepitant dimeglumine, which comprises,.
In a fourteenth embodiment, the present invention relates to a neutral form of fosaprepitant.
Thus, it appears that the conversion of fosaprepitant to aprepitant can occur in multiple tissues.
In a fifteenth embodiment, the application relates to a stable amorphous fosaprepitant dimeglumine.
In rabbits, fosaprepitant caused initial transient local acute inflammation following paravenous, subcutaneous and intramuscular administration.
Thus, there is a need in the art to provide intermediates of fosaprepitant in solid state.
Fosaprepitant dimeglumine intermediate, neutral fosaprepitant, and amorphous fosaprepitant dimeglumine and processes for their preparations.
In a fifteenth embodiment, the present invention relates to a stable amorphous fosaprepitant dimeglumine.
Effect of fosaprepitant on the pharmacokinetics of other active substances CYP3A4 inhibition.
In a third embodiment, the present invention provides an isolated, solid stable dibenzyl ester fosaprepitant.
How to buy Fosaprepitant dimeglumine powder, buy EMEND powder from AASraw.
In a ninth embodiment, the present invention provides a process for the purification of fosaprepitant dimeglumine, comprising,.
Concomitant administration of fosaprepitant with St. John' s Wort is not recommended.
