Examples of 'fviii' in a sentence
Meaning of "fviii"
'FVIII' is a noun that refers to Factor VIII, a protein in the blood that helps with blood clotting
How to use "fviii" in a sentence
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fviii
Fviii peptides and their use in tolerising haemophiliacs.
Study on the switch in recombinant fviii.
Persistence of fVIII inhibitors is associated with increased risks of morbidity and mortality.
Hemophilia a is a bleeding disorder caused by deficient or absent production of factor viii fviii.
Many natural and recombinant forms of fVIII have been isolated and generated.
Thrombin cleaves fVIII causing dissociation with VWF ultimately leading to fibrin formation through fIX.
Inhibitors neutralize the procoagulant activity of fviii and affect the treatment efficiency.
Furthermore, the disclosure is not limited to human fVIII.
These residues are conserved in mouse fVIII and porcine fVIII Fig.
This site is conserved in human, porcine and mouse fVIII.
In certain embodiments, the protein is a fVIII or fIX or variant thereof.
Therapeutic levels of fVIII can be achieved more rapidly by infusing the concentrated OBI-1 product.
The level of a patient 's antibody to porcine fVIII is different for each individual.
The cuticle bleeding times ( CBTs ) were measured to evaluate the efficacy of the fVIII products.
The treatment of ha is based on replacement of fviii, requiring exogenous fviii intravenous infusions.
See also
Five fviii - / - mice were injected with sterile heparinized citrated saline.
In certain embodiments, the fVIII variant comprises a deleted B domain.
FVIII levels were determined against a porcine fVIII standard designated HY98P.
The C2 domain is involved with fVIII binding to VWF.
Exemplary fVIII variants include the HSQ and ET3 variants.
FIG . 4 illustrates AAV vectors encoding fVIII variants.
A concentration of about 100 ng / ml for fVIII in the blood is considered in the normal range.
Fig . 1 Alignment of predicted amino acid sequences of human, porcine, and mouse fVIII.
Isolation of porcine fVIII cDNA clones containing the 3 ' half of the C2 domain codons.
In all cases, the plasmas were spiked to a predicted fVIII activity of 0.9 U / ml.
Isolation of porcine fVIII cDNA clones containing 5 ' UTR sequence, signal peptide and A1 domain codons.
FIG . 18 illustrates an AAV vectors encoding an fVIII variant.
The fVIII concentration in normal non-hemophilia A subjects is approximately 100 Units / dL.
The amino acid numbers in Fig . 1A-1H apply to human fVIII only.
OBI-1 was provided in sterile vials containing 535 Units of fVIII activity per vial.
HYATE, C was provided in sterile vials containing 541 IU of fVIII per vial.
