Examples of 'gene delivery vehicle' in a sentence
Meaning of "gene delivery vehicle"
Gene delivery vehicle: This phrase is used in molecular biology and genetics to refer to a mechanism or method used to introduce genetic material into cells for research or therapeutic purposes
How to use "gene delivery vehicle" in a sentence
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gene delivery vehicle
Transgenic progenitor cells serve as potent gene delivery vehicle.
A preferred gene delivery vehicle according to the invention is a recombinant adenovirus.
Such a vehicle is preferably a liposome or a viral gene delivery vehicle.
In another aspect an hPNQALRE gene delivery vehicle is derived from a togavirus.
Any suitable type of viral vector may be employed as a gene delivery vehicle.
In an aspect the hPNQALRE gene delivery vehicle is a recombinant retroviral vector.
The expression vector is preferably introduced into the cell vÃa a gene delivery vehicle.
In an embodiment a gene delivery vehicle is used to deliver a desired polynucleotide to a predetermined site.
The nucleic acid compound may be provided to a cell as part of a gene delivery vehicle.
The gene delivery vehicle may comprise a promoter and an hPNQALRE subgenomic polynucleotide.
The nucleic acid compound may be present as such in the gene delivery vehicle.
An hPNQALRE gene delivery vehicle can also be a recombinant adenoviral gene delivery vehicle.
The invention therefore further provides a vaccine comprising a gene delivery vehicle of the invention.
A gene delivery vehicle is any molecule that can carry inserted polynucleotides into a host cell.
An hPNQALRE subgenomic polynucleotide can be combined with a condensing agent to form a gene delivery vehicle.
See also
Thus the invention also provides a use wherein said gene delivery vehicle further comprises a suicide gene.
Alternatively . an hPNQALRE subgenomic polynucleotide can be with a liposome to form a gene delivery vehicle.
In another methods, an hPNQALRE gene delivery vehicle is derived from a togavirus.
Yet, it is clear that the phage has utility as a gene delivery vehicle.
In one aspect, the gene delivery vehicle comprises a promoter and an hPNQALRE subgenomic polynucleotide.
Use according to anyone of claims 4-6, wherein said gene delivery vehicle further comprises a suicide gene.
Provides a gene delivery vehicle according to the invention that has a different tropism than adenovirus 35.
That property is co-opted for use as a gene delivery vehicle in viral based vectors.
A gene delivery vehicle according to any of claims 1 to 7 which is a virus.
It is preferable that the recombinant viral gene delivery vehicle is a replication-defective recombinant virus.
A gene delivery vehicle according to any one of claims 1, or 3 for use as a pharmaceutical.
In a preferred embodiment, the HPNQALRE gene delivery vehicle is a recombinant retroviral vector.
A gene delivery vehicle according to claim 1, comprising an adenovirus serotype 35 penton and hexon.
Use according to any one of claims 4-11, wherein said gene delivery vehicle comprises a recombinant adenovirus.
Thus, the gene delivery vehicle cells may be used as an immunostimulant, immunomodulator, or vaccine.
Use according to claim 4-8, wherein said gene delivery vehicle has a tropism for fibroblast-like synoviocytes.
A gene delivery vehicle expressing the apoptosis-inducing proteins VP2 and / or apoptin.
For example, the gene delivery vehicle can be introduced by catheter see U. S.
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