Examples of 'gene disruption' in a sentence
Meaning of "gene disruption"
Gene disruption refers to the process of intentionally altering or disabling a specific gene within an organism, often used in genetic studies to understand the function of a particular gene.", "context": "Commonly used in the field of genetics and molecular biology.
How to use "gene disruption" in a sentence
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gene disruption
Methods of gene modification and gene disruption.
Cherry indicates gene disruption rates observed in transfected cells.
Comprising a thymidylate synthase gene inactivated by gene disruption.
Techniques for gene disruption are generally known in the art.
An example thereof is the lowering of the promoter activity by gene disruption.
Corresponding suitable gene disruption cassettes are known in the art.
Gene disruption and precursor molecules synthesized by the mutants constructed.
Others are working on treatments for cystic fibrosis and severe immunodeficiency using gene disruption.
A new efficient gene disruption cassette for repeated use in budding yeast.
This restores gene function and leaves only one copy of gene disruption cassette behind.
Other suitable sites for gene disruption or deletion are discussed elsewhere in the application.
The Kiani lab looks to control where and when this gene disruption occurs.
Gene disruption using homologous recombination can be carried out in accordance with a conventional method.
LTR inversion positions the gene disruption cassette into a mutagenic sense orientation.
The bars indicate the position of the four Pvul fragments analysed by gene disruption.
See also
Both classical and gene disruption techniques have resulted in strains with a reduced protease background.
We introduced elm1A into the above mutant strains by gene disruption.
We examined the effects of COMT gene disruption and COMT inhibition in acute pain models.
Gene disruption targeting at a gene encoding the enzyme ;.
In some embodiments, the gene disruption can include a complete gene deletion.
One possible means for rendering a gene non-functional is gene disruption.
Recent strategies, using gene disruption technologies, have produced mice that lack myoglobin.
The sialylated glycoform was found to be absent in strains containing a lic3A gene disruption.
The results of the targeted gene disruption experiments are summarized in Table 12.
Coupling endonucleases with end-processing enzymes drive high efficiency gene disruption.
Example 3, Effect of ybjE gene disruption on amino acid resistance of an Escherichia bacterium.
Neurochondrin negatively regulates CaMKII phosphorylation, and nervous system-specific gene disruption results in epileptic seizure.
Based on the obtained subclone a gene disruption vector was generated as described for A. sojae.
Preferably the recombinant yeast cell further comprises a gene disruption in Snf4.
Fig . 1, schematic view for the gene disruption by homologous recombination.
Transformation into S. pneumoniae results in duplication of the target fragment and subsequent gene disruption.
Preparation of arming yeast and gene-disrupted strains Gene disruption was performed in a conventional manner.
In some embodiments, DNA end-processing enzymes are provided to enhance the rate of gene disruption.
C, Target gene after Cre mediated inversion of the gene disruption cassette which causes the mutation.
Targeted gene disruption has wide applicability for research, therapeutic, agricultural, and industrial uses.
Non-coding DNA may perhaps serve to decrease the probability of gene disruption during chromosomal crossover.
Gene disruption was verified by using LIG4 and HIS3 primers in PCR.
The non-naturally occurring microorganism of claim 1 or 2, wherein said gene disruption comprises a gene deletion.
Confirmation of budA and 2,3bdh gene disruption using ClosTron group II insertional inactivation tool,.
Therefore, genomic engineering by CRISPR-Cas9 gives researchers the ability to generate targeted random gene disruption.
The PFI-013 gene disruption can also be inducible when certain conditions are present.
The non-naturally occurring microorganism of claim 3, wherein said gene disruption further comprise disruption of,.
Southern blot analyses conformed the presence of the desired prb1A,,HIS3 gene disruption.
Example 7, Preparation of orf1082 gene disruption strain and evaluation of DNA amplification capacity.
Fig . 7, Structure of the different molecules obtained by gene disruption.
The ver1 and ver2 primers are used to verify gene disruption by PCR.
Southern blot analyses confirmed the presence of the desired mnn9,, TRP1 gene disruption.
The yeasts deficient in GCY1 and / or YPR1 activity were prepared by gene disruption.
Non-homologous end joining ( NHEJ ), also referred to as gene disruption.
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