Examples of 'glucuronidation' in a sentence
Meaning of "glucuronidation"
Glucuronidation is a process in the liver where glucuronic acid is attached to a substrate, making it more water-soluble for easier elimination from the body
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- The reaction of a biological substance with glucuronic acid
How to use "glucuronidation" in a sentence
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glucuronidation
Estriol is metabolized via glucuronidation and sulfation.
The deacetylated metabolite was further metabolised by glucuronidation.
Ritonavir may induce glucuronidation of methadone.
The major elimination pathway in cats is glucuronidation.
Glucuronidation is the major metabolic pathway.
Raltegravir is eliminated primarily by glucuronidation in the liver.
Glucuronidation of a racemic compound yields a pair of diastereomeric glucuronides.
Not significantly inhibit or induce lamotrigine glucuronidation.
Major elimination pathways are glucuronidation as well as renal excretion.
The primary metabolism pathway of pitavastatin is glucuronidation.
This linkage process is known as glucuronidation or glucuronide conjugation.
Temazepam and oxazepam are largely eliminated by glucuronidation.
The major pathways are glucuronidation and ketone reduction.
Aripiprazole also does not undergo direct glucuronidation.
Glucuronidation of the parent compound is a major route of biotransformation.
See also
Effects of other medicinal products on glucuronidation of lamotrigine.
Glucuronidation and renal excretion of unchanged tigecycline are secondary routes.
Different functional groups may be subjected to glucuronidation.
Presystemic glucuronidation is exten sive.
Naproxen and other inhibitors of glucuronidation.
Minor metabolites due to glucuronidation and oxidation were also detected.
Biotransformation of curcumin through reduction and glucuronidation in mice.
First glucuronidation of medetomidine was studied without inhibitor compounds.
Three compounds were found to inhibit glucuronidation of medetomidine.
Glucuronidation occurs to a lesser extent.
Emtricitabine did not inhibit the enzyme responsible for glucuronidation.
Presystemic glucuronidation is extensive.
Firocoxib is metabolised predominantly by dealkylation and glucuronidation in the liver.
This is a glucuronidation reaction.
The oxidative metabolites are further metabolised by conjugation via glucuronidation.
The glucuronidation activity of liver microsomes was different between species.
Medicinal products metabolised by glucuronidation.
Glucuronidation in human liver microsomes like in rat liver microsomes is stereoselective.
Due to induction of lamotrigine glucuronidation.
Glucuronidation is the most important reaction in the conjugative drug metabolism.
Sometimes toxic substances are also less toxic after glucuronidation.
Glucuronidation is the most important drug metabolism reaction besides oxidations.
Metabolised in the liver by glucuronidation.
Glucuronidation of estradiol.
No other drugs that are believed to affect hepatic glucuronidation were administered.
The glucuronidation of the drug in the kidney also facilitates bile excretion.
No other drug that are believed to affect hepatic glucuronidation were administered.
Phenolic glucuronidation is the major phase II metabolic route.
Perampanel is extensively metabolised via primary oxidation and sequential glucuronidation.
Extent by glucuronidation.
This can be excreted via the urine directly or after glucuronidation.
Inducers of glucuronidation.
The elimination pathways of letermovir in vivo are biliary excretion and glucuronidation.
The main metabolic pathway of trichlorfon involves glucuronidation and further dehydrochlorination.
Apart from other pathways these products are further metabolized via glucuronidation.
