Examples of 'glycogen synthase' in a sentence
Meaning of "glycogen synthase"
glycogen synthase: An enzyme responsible for converting glucose into glycogen for storage in liver and muscle cells. It plays a crucial role in regulating blood sugar levels and energy metabolism in the body. It is commonly studied in biochemistry, physiology, or medical research
How to use "glycogen synthase" in a sentence
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glycogen synthase
Metformin stimulates intracellular glycogen synthesis by acting on glycogen synthase.
This action is mediated by glycogen synthase and phosphorylase of these tissues.
This activates glycogen phosphorylase and inhibits glycogen synthase.
The glycogen synthase is turned into a less active form and glycogen synthesis is inhibited.
Preferably the polypeptide increases the activity of hepatic glycogen synthase.
Evaluation of glycogen synthase activity Glycogen synthase activity was assayed as follows.
It was initially identified as an enzyme able to phosphorylate and hence inhibit glycogen synthase.
Glycogenolysis Glycogen synthase Glycogen storage disease.
By placing AMPK in close proximity to one of its substrates glycogen synthase.
Then, the enzyme glycogen synthase combines UDP-glucose units to form a glycogen chain.
This interaction appears to be regulated by glycogen synthase kinase 3 beta.
The active form of glycogen synthase increased until postnatal day 19 and then declined.
Glycogen phosphorylase is activated by phosphorylation, whereas glycogen synthase is inhibited.
They are selective Glycogen synthase kinase 3 inhibitors.
Moreover, adiponectin decreases glycogen concentration by reducing the activity of glycogen synthase.
See also
Heterocyclic compounds and their use as glycogen synthase kinase 3 inhibitors.
In addition, glucagon signalling activates glycogen phosphorylase and inhibits glycogen synthase.
GSK3 inhibits glycogen synthase by direct phosphorylation.
There is clinical and genetic evidence implicating glycogen synthase in type 2 diabetes.
Glycogen synthase kinase 3 ( gsk-3 ) is a highly conserved and ubiquitously expressed protein in several species.
The rate-limiting step in the glycogen synthesis is catalyzed by the enzyme glycogen synthase.
For example, the phosphorylation of glycogen synthase by protein kinase C stops the synthesis of glycogen.
The inhibition of GSK3 then triggers upregulation of glycogen synthase activity.
GSK-3 inactivates glycogen synthase through phosphorylation, to suppress incorporation of sugar into cells.
The cAMP-dependent protein kinase acts upon the the enzyme glycogen synthase by phosphorylating it.
Glycogen synthase activity is expressed as a percentage of the total synthase activity ( G6P maximum ).
GSK3 was originally identified as a kinase that inhibits glycogen synthase by direct phosphorylation.
In a further aspect, the glycogen synthase kinase ( GSK ) inhibitor is a GSK-3 inhibitor or a GSK-3B inhibitor.
Under resting conditions, GSK3 phosphorylates and inactivates glycogen synthase vÃa dephosphorylation.
Amyloid beta peptides, glycogen synthase kinase-3beta and cholinergic neurons,.
Glycogen storage disease type 0 is a disease characterized by a deficiency in the glycogen synthase enzyme GSY.
Thus, the dephosphorylation of glycogen synthase by PP1GL may be measured.
Normally, the presence of insulin causes inhibition of GSK-3-mediated phosphorylation and deactivation of glycogen synthase.
This has been attributed to dephosphorylation of glycogen synthase ( 3 ) by protein phosphatase 1.
GSK-3 is a ubiquitously expressed serine / threonine kinase that phosphorylates and inactivates glycogen synthase.
Figure 19 shows the construction of two glycogen synthase transformation vectors.
When GSK-3 is phosphorylated, it is deactivated, and prevented from deactivating glycogen synthase.
This data confirms the status of glycogen synthase as an enzyme with high Q10.
GSK-3B showed a high degree of specificity for glycogen synthase.
Detailed description of the invention The glycogen synthase kinase-3B ( GSK-3B ) is a serine-threonine protein kinase.
IPG P-type activates pryuvate dehydrogenase phosphatase and glycogen synthase phosphatase.
Human PASK ( hPASK ) phosphorylates glycogen synthase primarily at Ser-640, causing near complete inactivation.
In particular, the kinase is selected from protein kinase C or glycogen synthase kinase-3.
Two examples of such substrates include glycogen synthase kinase-3 ( GSK3 ) and Forkhead transcription factors ( FKs ).
The GSK3? is a serine / threonine multifunctional protein, which is able to phosphorylate and inactivate glycogen synthase.
H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors.
GSK-3 is responsible for phosphorylating ( and thus deactivating ) glycogen synthase.
The first Akt substrate identified was glycogen synthase kinase 3 GSK3 ; Cross et al ., Nature.
Figure 18 shows the nucleotide sequence for E coli glycogen synthase.
The term " CHIR " refers to a glycogen synthase kinase 3 ( GSK3 ) inhibitor which mimics Wnt signaling preadipocytes.
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Glycogen burns rapidly to provide quick energy
They promote glycogen storage in the liver
Glycogen is composed of a branched chain of glucose residues
