Examples of 'gpcrs' in a sentence
Meaning of "gpcrs"
gpcrs (noun): GPCRs stand for G protein-coupled receptors which are a type of protein receptor involved in cell signaling
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- plural of GPCR
How to use "gpcrs" in a sentence
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gpcrs
A number of GPCRs have yet to be fully characterized.
No clear functions have been assigned to the GPCRs.
A significant number of GPCRs targets are yet to be commercially exploited.
There is a specialised database for GPCRs.
Regulation of GPCRs by their alternative proteins.
The scientists did not choose to explore GPCRs accidentally.
All GPCRs are included in the scope of the invention.
Aspartate is conservatively placed in several GPCRs.
One characteristic of adhesion GPCRs is their extended extracellular region.
The GPCRs constitute the largest known protein superfamily.
Crystallization of membrane proteins including GPCRs remains a challenge.
Adhesion GPCRs are found in fungi.
The hydrophilic sockets are surrounded by hydrophobic residues of the GPCRs.
Active phosphorylated GPCRs recruit arrestin to the plasma membrane.
Prostaglandins exert their effects by interacting with specific GPCRs.
See also
Such GPCRs are found in nature.
This is exemplified by GPCRs.
How GPCRs influence inflammation.
Efforts to obtain and crystallize GPCRs are therefore of great importance.
It will then compare these profiles with those of mutant GPCRs.
Ligands of orphan GPCRs may be identified from biological samples.
Molecular pharmacology of GPCRs.
It is a common finding that GPCRs regulate cell cycle progression.
The general procedure for expression of the disclosed GPCRs is as follows.
But expression of most GPCRs is difficult to be achieved in most hematopoietic cells.
The dopamine neurotransmitter mediates synaptic transmission by binding to five specific GPCRs.
Glutamate receptors form a group of GPCRs that are important in neurotransmission.
The invention is particularly suitable for investigating the pharmacology of the GPCRs.
But expression of GPCRs on the surface of heterologous cells is extremely low.
About a third of all drugs on the market are designed to bind with GPCRs.
These versions of human GPCRs can also be utilized in research settings.
There are no conclusive data to indicate how large the oligomers of functional GPCRs are.
Sequence comparisons with other GPCRs also revealed a degree of identity.
Any cellular response related to the activity of the selected GPCRs is encompassed.
Alternative trafficking itineraries for GPCRs determine which signaling pathways are activated.
Project activities should help shed light on the mechanism of action of these GPCRs.
These taste cell specific GPCRs are components of the taste transduction pathway.
Mediated by GPCRs.
A number of adhesion GPCRs may have important roles within the immune system.
This activation process can be modulated by the binding of many other partners of GPCRs.
Signaling through GPCRs is instrumental in the pathology of a large number of diseases and disorders.
Signal transduction mediated by the superfamily of GPCRs dates back to the origin of multicellularity.
The transmembrane part is highly homologous with other members of the rhodopsin family of GPCRs.
Also disclosed is the use of the altered GPCRs for screening therapeutic compounds.
GPCRs are involved in a wide variety of physiological processes.
There have been very few and rare reports of GPCRs localising in the nucleus.
Known and uncharacterized GPCRs currently constitute major targets for drug action and development.
Protein binding domains stabilizing functional conformational states of GPCRs and uses thereof.
This phenomenon is well established for other GPCRs and complicates the development of pharmaceutical drugs.
The experimental evidence for the nuclear localization and signalling of GPCRs will be reviewed.
