Examples of 'grazoprevir' in a sentence
Meaning of "grazoprevir"
grazoprevir (noun): A medication belonging to the class of drugs known as hepatitis C virus (HCV) protease inhibitors, used in combination with other antiviral agents for the treatment of chronic HCV infection
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- An experimental drug for the treatment of hepatitis C.
How to use "grazoprevir" in a sentence
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grazoprevir
This change is not clinically relevant for grazoprevir.
Elbasvir and grazoprevir are not expected to be removed by peritoneal dialysis.
Haemodialysis does not remove elbasvir or grazoprevir.
Grazoprevir has been shown to cross the placenta in rats and rabbits.
Boosted darunavir may increase the exposure to grazoprevir.
Carcinogenicity studies for grazoprevir and elbasvir have not been conducted.
Zepatier contains the active substances elbasvir and grazoprevir.
It is unknown whether elbasvir or grazoprevir and their metabolites are excreted in human milk.
Darunavir with low dose ritonavir may increase the exposure to grazoprevir.
No circulating metabolites of either elbasvir or grazoprevir were detected in human plasma.
Based on theoretical considerations REZOLSTA may increase the exposure to grazoprevir.
No human data on the effect of elbasvir and grazoprevir on fertility are available.
ZEPATIER is an antiviral medicine that contains the active substances elbasvir and grazoprevir.
And grazoprevir concentrations, leading to.
Available pharmacokinetic data in animals has shown excretion of elbasvir and grazoprevir in milk.
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Grazoprevir concentrations were greatly increased when co-administered with atazanavir / ritonavir.
You are taking hepatitis C antiviral agents such as elbasvir or grazoprevir used to treat hepatitis.
Elbasvir and grazoprevir is not approved for use by anyone younger than 18 years old.
Boosted PREZISTA may increase the exposure to grazoprevir.
Grazoprevir is not a P-gp inhibitor based on in vitro data.
The active substances are, elbasvir and grazoprevir.
Elbasvir and grazoprevir are not OATP1B inhibitors in humans.
Concomitant administration of glecaprevir, pibrentasvir, elbasvir or grazoprevir see section.
Elbasvir and grazoprevir are partially eliminated by oxidative metabolism, primarily by CYP3A.
Elbasvir is not a CYP3A inhibitor in vitro and grazoprevir is a weak CYP3A inhibitor in humans.
Co-administration with grazoprevir did not result in clinically relevant increases in exposures of CYP3A substrates.
Zepatier is available as tablets which contain 50 mg elbasvir and 100 mg grazoprevir.
Zepatier combines elbasvir and grazoprevir and like Harvoni, has few side effects.
Grazoprevir is a substrate of OATP1B drug transporters.
Protease inhibitor, Elbasvir / grazoprevir.
The potential for grazoprevir to be a breast cancer resistance protein ( BCRP ) substrate can not be excluded.
Grazoprevir is a second generation hepatitis C virus protease inhibitor acting at the NS3/4A protease targets.
Both elbasvir and grazoprevir bind to human serum albumin and 1-acid glycoprotein.
Grazoprevir is transported by the solute carrier proteins SLCO1B1 and SLCO1B3.
Elbasvir and grazoprevir are substrates of CYP3A and P-gp.
Effectively grazoprevir prevents cleavage of the necessary polyproteins for replication . [ 9 ].
Elbasvir or grazoprevir ( used to treat hepatitis C virus infection ).
