Examples of 'half-maximal' in a sentence
Meaning of "half-maximal"
half-maximal (adjective) - In biology or pharmacology, the term 'half-maximal' refers to the point at which a response or effect is halfway between its minimum and maximum levels. It is often used to describe the concentration of a drug or stimulation needed to produce a response
How to use "half-maximal" in a sentence
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half-maximal
Drug concentration that causes half-maximal effect.
A half-maximal collagen concentration was chosen for further experiments.
We calculated the concentrations required for half-maximal survival.
A half-maximal dose of hCG may then be readily determined.
A concentration of oxytocin giving at least half-maximal response was selected.
Arrows denote half-maximal inhibition points for each curve.
The concentration of glucose at which GK demonstrates half-maximal activity is approximately 8 mM.
The half-maximal receptor activation for the various agonist ligands is summarized.
The concentrations of bispecific antibodies at half-maximal binding are determined reflecting the respective KDs.
At about 1 µM, proliferation was reduced to its half-maximal value.
The concentration for half-maximal binding is reported as a measure of relative binding affinity.
The antibody concentration necessary to achieve half-maximal binding is called EC50.
The half-maximal inhibitory concentration or IC50 was then determined.
The concentration of test compound required to produce a half-maximal increase in coronary flow is determined.
A half-maximal inhibitory effect of EGF-URO was observed at a concentration of about 1 nM.
See also
This is a standard technique that also provides half-maximal binding information following dose response measurements.
ED50 values were taken as the concentration of agonist that produced half-maximal contraction.
The concentration producing half-maximal inhibition was calculated as the IC50.
The IC50 is the concentration of compound which causes a half-maximal blocking effect.
The substrate concentration at half-maximal rate is known as the Michaelis constant ( KM ).
The EC50 is the concentration of the molecule which evokes a half-maximal effect.
The concentrations of BCMA/CD3 bispecific antibodies at half-maximal binding were determined reflecting the respective KDs.
Calculated half-maximal binding concentrations for all experiments are summarized in Table 13.
The IC50 is the concentration of molecule which causes a half-maximal blocking effect.
EC50 values at half-maximal binding for binding to human and murine FAP are being determined.
The EC50 is the concentration of a compound which causes a half-maximal mimicking effect.
The PaO2 at which half-maximal oxygen saturation of total hemoglobin occurs is termed the P50 value.
The IC50 value was determined by the concentration causing a half-maximal percent activity.
Half-maximal inhibition was found at about 1 ng / ml.
The concentration of dronedarone causing a half-maximal inhibition of late Na+ was calculated to be 4 µM.
KM, the Michaelis constant, is the concentration of substrate that leads to half-maximal velocity.
The concentration producing the half-maximal effect was then calculated as EC50.
IC50 is that concentration of inhibitors which reduces the activity of PASK to half-maximal level.
The concentration producing the half-maximal effect is then calculated as EC50.
The half-maximal effect was obtained for 10 µM astemizole.
It is understood that another designation for IC50 is the half-maximal inhibitory concentration.
The half-maximal haemolytic concentration of sodium lauryl sulfate is 22+4 ppm.
The concentration of calcium required for half-maximal hydrolyses of both polyphosphoinositides was about 1?M.
Half-maximal binding of the IgGb12 antibody was achieved at a concentration below 1 µg / ml of antibody.
The concentration of agonist that produced a half-maximal response is represented by the EC50 value.
The half-maximal cytostatic inhibition of endothelial cell proliferation was at approximately 100 pg / ml.
There was no change in the glucose concentration required for half-maximal rates of 14CO2 production.
The positive control gave half-maximal neuronal survival at a concentration of 1.1 mg / ml.
The EC50 value was determined by the concentration causing a half-maximal percent efficacy . Results.
Half-maximal prolongation of the aPTT was achieved with about 100 nM antibody.
The concentration of test peptide that results in a half-maximal absorbance is recorded as the EC50.
The half-maximal effect of VEGF was obtained at 5ng/ml.
Solubilization decreased the concentrations of Mg2 + required for half-maximal velocity and for saturation.
The magnitude of the half-maximal inhibitory concentration ( IC 50 ) is deduced therefrom.
Activity was sensitive to ionic strength, with half-maximal inhibition at 70 mM NaCl.
