Examples of 'hcmv' in a sentence
Meaning of "hcmv"
hcmv (noun): an abbreviation for Human Cytomegalovirus, a common virus in the herpes virus family that can cause mild to severe symptoms, especially in individuals with weakened immune systems
How to use "hcmv" in a sentence
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hcmv
The antibodies of the invention are able to neutralise hCMV.
However the target of hCMV neutralising antibodies remains to be established.
The antibodies have particularly high potency in neutralizing hCMV.
A hCMV immediate early promoter sequence can be obtained using known methods.
The antibodies may bind to an epitope formed by a single hCMV protein.
A donor with high hCMV neutralising antibody titres in the serum was identified.
Two viral glycoprotein complexes are believed to control the cellular tropism of hCMV.
A suitable hCMV promoter sequence could also be isolated from an existing plasmid vector.
This experiment clearly shows that there is transactivation of the hCMV promoter.
The hcmv disease in these patients can accelerate the progression of aids and death.
The invention provides antibodies having particularly high potency in neutralizing hCMV.
Particularly preferred diseases are viral diseases such as hCMV infection and malignant diseases.
Recently two viral glycoprotein complexes have been shown to control the cellular tropism of hCMV.
The antibodies of the invention are able to neutralise hCMV infection of several cell types.
The invention relates to monoclonal or recombinant antibodies having particularly high potency in neutralising hCMV.
See also
Number of methylated CpG site of the hCMV promoter / enhancer obtained from different cell lines.
The gene for the light chain was under the control of the hCMV promoter.
For hypoxia-induced expression, the hCMV promoter is replaced by a promoter containing at least one HRE.
PCILux expresses peroxisomal luciferase under control of the hCMV IE promoter.
Accordingly, novel hCMV Intron A fragments and methods of using the same have been disclosed.
A second antibody, or antigen binding fragment thereof, which binds to the hCMV protein gB.
A representative hCMV enhancer / promoter region is shown in Figure 2.
Clearly the gpCMV vector was at least two-fold more active luciferase than the hCMV plasmid.
Among these promoters, a hCMV promoter and a SV40 promoter are preferred.
The invention provides a neutralising human monoclonal antibody, wherein the antibody recognises an antigen from hCMV.
Hatched bars, with known hCMV enhancer.
This may be due to, for example, infection with an anti-viral resistant strain of hCMV.
In a preferred embodiment, the native hCMV immediate early promoter sequence comprises SEQ ID NO, 1.
Shows an experiment comparing the new IE2 enhancer with the known hCMV enhancer.
The resulting expression plasmid, pCON3, contains the hCMV enhancer / promoter region with a 130 bp Intron A fragment.
The 235-kbp genome of mCMV also lacks large internal and terminal repeat characteristics of hCMV.
Example 1, Cloning of B cells and screening for hCMV neutralising activity.
Plasmid pEVhis10 was derived from pEVhis14 by deleting a BamHI fragment that contains the hCMV enhancer / promoter.
SEQ ID NO, 03-Nucleotide sequence of strand A of the hCMV promoter / enhancer, completely deaminated.
Balb / C mice were immunized in a prime-boost-boost regimen with hCMV antigens.
The well known SV40 enhancer or the hCMV enhancer.
The tetO-HuPrP fragment is then cloned into vector pBS226 behind the hCMV promoter.
