Examples of 'hedgehog signaling' in a sentence
Meaning of "hedgehog signaling"
hedgehog signaling - A biological process in which cells communicate to regulate growth, development, and tissue repair. Named after the hedgehog gene, this signaling pathway plays a crucial role in embryonic development
How to use "hedgehog signaling" in a sentence
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hedgehog signaling
Hedgehog signaling remains important in the adult.
These substances inhibit the hedgehog signaling pathway.
Hedgehog signaling in cartilage neoplasia and development.
Cyclic sulfonamide containing derivatives as inhibitors of hedgehog signaling pathway.
Hedgehog signaling pathway for breast cancer identified.
The biochemical role of patched in the hedgehog signaling pathway is unclear.
Hedgehog signaling has been implicated in a wide variety of cancers and carcinogenesis.
The invention also provides methods of inhibiting hedgehog signaling activity in a cell.
Hedgehog signaling is essential in many stages of development, especially in formation of left-right symmetry.
All eight cell lines examined express genes involved in hedgehog signaling.
Most of what is known about hedgehog signaling has been established by studying SHH.
The encoded protein may function as a tumor suppressor in the hedgehog signaling pathway.
The Hedgehog signaling pathway is a well-known regulator of organ development.
More specifically the aminoproline derivatives are envisaged to agonize ptc inhibition of hedgehog signaling.
For example, ineffective Dhh hedgehog signaling in mice leads to viable but sterile mice.
See also
Applicants have herein identified certain kinases necessary for effective hedgehog signaling.
Figure 5A shows a schematic of activation of the hedgehog signaling pathway in the Luciferase reporter assay.
A library of drugs was previously tested in humans for agents that antagonize Hedgehog signaling.
Patent Literature ( PTL ) 4 discloses, as a hedgehog signaling inhibitor, a piperazine compound having a furylcarbonyl piperazine structure.
These methods involve contacting the cells with an agent that inhibits hedgehog signaling pathway.
For example, Wnt, Notch, and Hedgehog signaling pathways are proposed features of CSCs.
The tumor cell is usually one that is responsive to Hedgehog signaling.
Itraconazole and analogs thereof inhibited pro-fibrotic Hedgehog signaling in rat hepatic stellate cells.
One particularly relevant pathway in which cholesterol takes place is the Hedgehog signaling pathway.
Zinc deficiency linked to activation of Hedgehog signaling pathway.
Next, we utilized the MAC-tag approach to map the interactome of the mammalian Hedgehog signaling.
SHH is the best studied ligand of the hedgehog signaling pathway.
In one method the bioactive agents modulate Wnt / B-catenin signaling, Notch signaling or Hedgehog signaling.
High PKA activity has been shown to antagonize hedgehog signaling in these systems.
For example, basal cell carcinoma cells are associated with active hedgehog signaling.
Using this Daoy cell model system, potent inhibitors of hedgehog signaling pathways can be identified.
Furthermore, as outlined above, cholesterol is an important aspect in Hedgehog signaling.
One such example of gene survival is the so-called hedgehog signaling pathway.
In another aspect, the invention provides a method of inhibiting hedgehog signaling activity in a cell.
It is also contemplated that the cell has a substantially wild-type hedgehog signaling pathway.
In some embodiments, the hedgehog inhibitor inhibits the Sonic hedgehog signaling pathway.
In some embodiments, the hedgehog inhibitor inhibits the Desert hedgehog signaling pathway.
In some embodiments, the hedgehog inhibitor inhibits the Indian hedgehog signaling pathway.
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Examples of using Hedgehog
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You even put this hedgehog on my head
If a hedgehog wants to be close with other hedgehogs
I feel like there is a hedgehog living in my knickers
Examples of using Signaling
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Audible signaling of selected events in the system
Someone out there is signaling to the house
Signaling an increase in blood flow to that area
