Examples of 'heterologous antigen' in a sentence
Meaning of "heterologous antigen"
heterologous antigen: A type of antigen that is foreign to the immune system, triggering an immune response
How to use "heterologous antigen" in a sentence
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heterologous antigen
In certain embodiments the heterologous antigen is an alphavirus antigen.
The heterologous antigen is preferably from a bacterium or virus.
The attenuated bacterium optionally expresses a heterologous antigen.
The heterologous antigen is preferably the wild type antigen.
Polypeptides according to the invention bound to the heterologous antigen.
The heterologous antigen may be presented by any suitable method.
Novirhabdoviruses thus have many advantages as heterologous antigen expression vectors.
The heterologous antigen may be a complete protein or a part of a protein containing an epitope.
Such herpetic virus light particles can carry a heterologous antigen.
The DNA encoding the heterologous antigen is expressed from a promoter that is active in vivo.
Control mice were immunized with TIRIVs without the heterologous antigen.
Nucleic acids encoding more than one heterologous antigen can be packaged in the CMV vector.
An attenuated bacterium of the invention may be capable of expressing a heterologous antigen.
A CMV vector that encodes a heterologous antigen is by definition a recombinant CMV vector.
Accordingly a vaccine can comprise a light particle from a variant according to the invention carrying a heterologous antigen.
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The DNA encoding the heterologous antigen in the recombinant CMV vector can also include a promoter.
In specific embodiments, a molecule of interest is a heterologous antigen.
In specific aspects, the heterologous antigen is an immunogen.
According to a specific embodiment, a molecule of interest is a heterologous antigen.
In specific embodiments, the heterologous antigen is an immunogen.
According to the present invention, the polypeptide is bound to the heterologous antigen.
In another embodiment, the heterologous antigen is an immunogenic peptide.
In one embodiment, the modified bacterium expresses a heterologous antigen.
In another embodiment, the heterologous antigen is bound to a vector particle.
In another aspect, each said nucleic acid molecule encodes a heterologous antigen.
Overlapping peptides of the heterologous antigen are generated by oligo-peptide synthesis.
In some embodiments, the first nucleic acid encodes a selection marker or a heterologous antigen.
The vector of claim 1, wherein the heterologous antigen comprises a cancer antigen.
The pharmaceutical composition according to claim 1, wherein the polypeptide is fused to the heterologous antigen.
The polynucleotide of claim 8, wherein the heterologous antigen is human mesothelin.
Preferably, the heterologous antigen is a membrane protein, more preferably an outer membrane protein.
Polypeptides according to the invention - heterologous antigen conjugates.
In some cases, the heterologous antigen is expressed on the surface of the yeast.
In still another embodiment, the polypeptide is bound to a vector particle containing the heterologous antigen.
In still another preferred embodiment, the heterologous antigen is a non-protein antigen.
The heterologous antigen may be non - Listerial.
Polypeptides according to the invention - heterologous antigen fusion proteins.
Preferably, the heterologous antigen is immunogenic when it is presented in the OMV.
In some embodiments, the recombinant RhCMV and HCMV vectors do not include a heterologous antigen.
However, in some embodiments, the heterologous antigen is a variant of a wild type antigen.
By heterologous antigen is meant any antigen that is not normally expressed by V. cholerae.
Research indicates for the soluble heterologous antigen utilization, mainly strongyloides venezuelensis.
Bacteria One aspect of the invention relates to a mutant bacterium, which expresses a heterologous antigen.
In some embodiments, the heterologous antigen does not comprise an EphA2 antigenic peptide.
The use of claim 13, wherein the vaccine further expresses a heterologous antigen.
In some embodiments, the heterologous antigen is a tumor antigen or is derived from a tumor antigen.
Preferably, one dose of a composition of the present invention comprises 25 µg of the heterologous antigen.
In a preferred embodiment, the heterologous antigen comprises a pathogen-specific antigen or a cancer antigen.
In this experiment, the malaria antigen UK39 served as the heterologous antigen.
In one particular embodiment, the heterologous antigen is contained inside the VIP.
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Examples of using Heterologous
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They may also be heterologous nucleic acids
The heterologous genes can vary as desired
These genes can be of heterologous or homologous origin
