Examples of 'hinge region' in a sentence
Meaning of "hinge region"
This phrase refers to a specific part or area of an object or structure that acts as a hinge. It indicates the region that enables movement, rotation, or pivoting in a mechanical or metaphorical sense
How to use "hinge region" in a sentence
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hinge region
Said hinge region is defined in this way.
Effects of mutations in the hinge region of serpins.
A hinge region domain may also be included.
At the opposite from the hinge region.
A hinge region domain may also be included if desired.
Some isotypes are further comprised of a hinge region.
The hinge region is indicated generally.
Preferably a scaffold protein has no hinge region.
The IgD hinge region.
The antibodies can bend in the hinge region.
However the hinge region may be shortened or lengthened as required.
Chimeric antigen receptors with an optimized hinge region.
The dimerization domain has a hinge region in some embodiments.
Fc fusión proteins may contain an immunoglobulin hinge region.
The hinge region is a particularly variable element of immunoglobulin structure.
See also
Some isotypes can also include a hinge region.
The hinge region is underlined.
The antibody can optionally include a hinge region.
Lacks a hinge region.
The altered constant region lacks a hinge region.
Changes within the hinge region also affect effector functions.
The variant constant region lacks a hinge region.
Particular sequences of hinge region of the disclosed immunoglobulins are the following.
This region has been termed the hinge region.
The hinge region is facing the wings in proximity to the incurved region.
Also described is amino acid modification in the hinge region.
The hinge region is preferably provided adjacent the common support member.
Encompasses also are amino acid modification in the hinge region.
Disulfide bonds in the hinge region connect the two heavy chains.
Further encompassed are amino acid modifications in the hinge region.
The coupling occurs at the hinge region of the antibody vÃa thioether linkages.
The mouse may lack a sequence encoding a hinge region.
The sequence of the hinge region of the homodimeric starting proteins may vary.
Further encompassed are amino acid modification in the hinge region.
The present invention may include a hinge region that allow a dimer formation.
Another important region of the heavy chain is the hinge region.
The hinge region is a region highly sensitive to a proteolytic enzyme such as papain or pepsin.
The latter is linked to the catalytic domain by a flexible hinge region.
The hinge region herein may be a native sequence hinge region or a variant hinge region.
The nucleic acid sequence encoding the hinge region is underlined.
The hinge region cysteine can be used as a modification site of polyethylene glycol described later.
Effector function can also be influenced by mutations in the hinge region.
The length and flexibility of the hinge region varies among the IgG subclasses.
The disclosure provides bispecific antibodies comprising a chimeric hinge region.
The hinge region refers to various structural segments of the heavy chain of IgG molecules.
The antibody according to the invention is devoid of hinge region disulfides.
The length of the upper hinge region correlates with the segmental flexibility of the antibody.
In a preferred embodiment the linker peptide is a hinge region sequence of an antibody.
Examples of sequences encoding flexible hinges are found in the immunoglobulin heavy chain hinge region.
Such a free sulfhydryl group may be located in the hinge region of the antibody component.
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Examples of using Hinge
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Insert center hinge pin and tighten
Hinge system with security for cleaning
Remove center hinge bracket by removing screws
Examples of using Region
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The reports from the region were horrifying
The region is constructing buildings to house migrants
An example of such a region is the shelf boundary
