Examples of 'human fcrn' in a sentence
Meaning of "human fcrn"
Human FCRN: This phrase likely refers to the Human Neonatal Fc Receptor (FCRN), a protein involved in immune responses and antibody transport in the human body
How to use "human fcrn" in a sentence
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human fcrn
Soluble human FcRn was expressed by the following procedure.
Assessment of the binding to human FcRn.
Human FcRn is coupled to a sensor chip using an amine coupling kit.
Assessment of the plasma retention in human FcRn transgenic mice.
The preferred human FcRn-binding domain is a region that directly binds to human FcRn.
Assessment for the plasma retention in human FcRn transgenic mice.
Human FcRn extracellular domain was treated by PNGaseF to remove N-linked sugars.
In one embodiment the antibody molecules of the present invention block human FcRn activity.
As a result, expressions of the human FcRn gene and the human FcgRIIb gene were detected.
Serum concentrations of WT and variants of antibodies in human FcRn knockin mice.
Human FcRn can be coupled to a CM5 chip using standard chemistry.
There are species differences between mouse FcRn and human FcRn Proc.
Antibodies were tested for binding to human FcRn at pH 6.0 by Biacore as described above.
The periplasmic fractions were used in an ELISA against a dilution series of human FcRn.
Relative binding of variant Fc immunoadhesins to human FcRn as determined by Biacore.
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In particular, preferred antigen-binding molecules includes a region that binds to human FcRn.
Oligo-DNA primers were prepared based on the human FcRn gene sequence disclosed J. Exp.
The ligand immobilization level of the surface was 890 RU human FcRn.
The extracellular domain of human FcRn alpha chain is provided in SEQ ID NO, 48.
Binding affinity of variants of the present invention to human FcRn at pH6.0.
Bolus injection of 10 mg / kg to human FcRn transgenic mice.
FIG . 32 shows a model of the human Fc domain in complex with human FcRn.
Relative binding of variant IgG1 anti-VEGF antibodies to human FcRn as determined by Biacore.
The modular antibody according to claim 1 or 2, wherein the antibody binds to human FcRn receptor.
In a specific embodiment, the binding affinity for human FcRn is increased about 170 fold.
In the following Table retention times of < VEGF-ANG-2 > bispecific antibodies on human FcRn are given.
Binding affinities of CTLA4-lg proteins to human FcRn at pH 6.0 Immunoadhesin.
Binding affinities of CTLA4-Ig proteins to human FcRn at pH 6.
Oligo-DNA primers were prepared based on the published human FcRn gene sequence J. Exp.
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Soluble human FcRn was expressed by the following procedure
Fc variants with altered binding to FcRn
The FcRn binding partner is conjugated with an antigen
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