Examples of 'human hepatocytes' in a sentence
Meaning of "human hepatocytes"
Human hepatocytes: Liver cells found in the human body
How to use "human hepatocytes" in a sentence
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human hepatocytes
Use of primary cultures of human hepatocytes in toxicology studies.
These cells were highly homogenous and similar to human hepatocytes.
Human hepatocytes were successfully used in cellular toxicity studies of PPARa agonists.
Isolation and purification of human hepatocytes.
Human hepatocytes work in the present invention and may be preferred in some situation.
Suspensions of cryopreserved human hepatocytes were used.
The compounds disclosed herein display significant functional antagonism of glucose production in human hepatocytes.
Previous studies have demonstrated that primary human hepatocytes are susceptible to apoptosis induced by FasL.
The present compounds had low toxicity on cultured human hepatocytes.
The data from in vitro studies with human hepatocytes indicated that tipifarnib undergoes direct glucoronidation.
Recombinant retroviruses have been used to deliver genes to human hepatocytes ex vivo.
SHBG causes lipolysis in human hepatocytes Cell culture experiments.
The in vitro drug metabolism data for histrelin were obtained using human hepatocytes.
Human hepatocytes Clint.
Methods for producing cells having a phenotype of primary human hepatocytes and compositions.
See also
In brief, cryopreserved human hepatocytes were thawed rapidly and diluted slowly with cell culture medium.
As a control cryopreserved / thawed human hepatocytes were used.
Obtained human hepatocytes were further investigated in the 3D liver tissue platform.
Long-term culture of rat and human hepatocytes.
Normal human hepatocytes were purchased from Clonetics, San Diego, CA and processed immediately upon delivery.
Stability of fully functional, mature human hepatocytes on biomatrix scaffolds.
In another embodiment, said hepatitis pseudo-virus replicates in vitro in human hepatocytes.
After infection, the sporozoites enter human hepatocytes and develop into hypnozoites.
In vitro studies showed negligible transporter-mediated uptake of cladribine into human hepatocytes.
In vitro, the uptake of palbociclib into human hepatocytes occurred mainly via passive diffusion.
Figure 13 is a set of graphs showing the inhibition of HCVpp infection in primary human hepatocytes.
Rucaparib down regulated CYP2B6 in human hepatocytes at clinically relevant exposures.
Due to their specific properties, pluripotent stem cells represent a credible alternative to primary human hepatocytes.
Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin, J.
In vitro studies indicated that carfilzomib did not induce human CYP3A4 in cultured human hepatocytes.
The current gold standard, primary human hepatocytes (PHHs), suffer from poor availability and high variability.
Tipiracil hydrochloride was not metabolised in human liver S9 or in cryopreserved human hepatocytes.
Furthermore, primary human hepatocytes do not express GLUT1.
Figure 15 is a line graph depicting the intracellular accumulation of L-dC in primary human hepatocytes.
Exposure of primary mouse, rat, and human hepatocytes to CO inhibited TNF-a induced apoptosis.
This example demonstrates successful transplantation of the immunocompromised, scid / bg / Alb-uPA mice with human hepatocytes.
The results indicated that primary human hepatocytes were capable of supporting HEV propagation ( Figure 4 ).
The role of TNF-a as a mediator of SREBP-1 maturation was investigated in human hepatocytes.
In vitro metabolism studies using human hepatocytes indicate that rosuvastatin is a poor substrate for cytochrome P450.
However, no continuously replicating culture of non-neoplastic, adult human hepatocytes has ever been established.
Primary human hepatocytes were obtained from Lonza ( Walkerville, Maryland ).
Table 2, Stability in rat and human hepatocytes.
Preferably, the human hepatocytes are injected intrasplenically, e . g ., into the inferior splenic pole.
Results Table . t1/2 of androgens of the invention after incubation with human hepatocytes.
The human hepatocytes were supplied by Biopredic in 24-well plates.
The toxic potential of compounds was investigated in vitro using primary human hepatocytes ( HEPG2 ).
Primary human hepatocytes were isolated and cultured as described by David, 1998.
This absence of de-iodination was further confirmed by stability tests using human hepatocytes ( see EXAMPLE 4 ).
Fresh normal human hepatocytes were maintained in Hepatocyte Culture Medium . ( a . ).
ApoB secretion may be different in rat hepatocytes, HepG2 cells and human hepatocytes in-vivo.
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Examples of using Hepatocytes
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But over half his hepatocytes are dead
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