Examples of 'human kappa' in a sentence
Meaning of "human kappa"
Human kappa: A term that may refer to a specific type of protein associated with immune function or a scientific classification system, depending on the context
How to use "human kappa" in a sentence
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human kappa
Preferably human kappa chain domains are used.
That already contains the human kappa region.
Human kappa light chain constant region.
The light chain constant region is human kappa.
Human kappa constant region.
Ck is the constant region of the human kappa light chain.
Briefly, human kappa receptors can be obtained from guinea pig cerebellar membranes.
The expression vector provided the human kappa constant region.
Human kappa LC = Sequence encoding immunoglobulin kappa light chain.
Three YACs were identified that spanned the human kappa loci.
In one aspect only the human kappa VJC locus is inserted.
This vector has included mycophenolic acid resistance gene and the human kappa constant region.
Comprises a human kappa light chain ; and.
In some aspects the signal or leader sequence comprises ompA or a human kappa leader sequence.
In some such methods, the human kappa light chain locus is the inserted KCo5 transgene.
See also
The KM mouse contains a human heavy chain transchromosome and a human kappa light chain transgene.
The primer mixes used for the human kappa splicing are described in detail in Table 6.
L6 mice contain an inserted human heavy chain and an inserted human kappa light chain.
A transcription unit for a human kappa ( k ) light chain, composed of.
In one embodiment, the murine light chain V region is fused to a human kappa light chain.
Moreover, they carry a human kappa light chain transgene, KCo5, as described in Fishwild et al.
The human light chain constant region preferably is a human kappa light chain constant region.
The mouse carries a human kappa light chain transgene, KCo5, as described in Fishwild et al.
Samples with the following final concentrations of mouse anti human kappa light chains were prepared,.
Each strain carried a human kappa light chain transgene, KCo5, as described in Fishwild et al.
The CDR-grafted LC variable region was attached to a human kappa constant region.
YK2, was the human kappa light chain containing YAC.
Optionally, the murine light chain V region is fused to a human kappa light chain.
Ii a human kappa light chain comprising the amino acid sequence of SEQ ID NO, 14.
Positive plaques were identified using the human kappa constant region gene as probe.
This human kappa light chain sequence has the same canonical classes for CDR-L2 and L3.
Human lambda chain was detected, but human kappa chain was not detected.
SEQ ID NO, 35 human kappa constant light chain amino acid sequence.
The CDR-grafted OKT4A light chain was constructed with the human kappa constant domain.
Ii a human kappa light chain comprising SEQ ID NO, 14.
For the light chain, the genomic human kappa constant region was used.
The immunoglobulin of claim 1, further comprising a human IgG1 constant region and a human kappa constant region.
DNA - and protein-sequence of the human kappa 8 light chain, variable region.
FIG . 14 depicts the DNA and amino acid sequence of human kappa constant region.
SEQ ID NO, 57 human kappa light chain constant region.
For the I chain, the vector contained the human kappa constant exon.
In preferred embodiments the antibodies comprise a human kappa light chain and a human IgG1 heavy chain.
Optionally, the antibody is a human kappa IgG1 antibody.
A humanized antibody according to claim 11, having all human kappa 1 consensus light chain framework residues.
Assay plates were coated with a human kappa chain specific antibody ( BD ).
This was ligated to the 5 ' NarI end of the human kappa constant domain DNA.
After splicing, the variable region becomes fused to a human kappa constant region exon ( see Figure 7 ).
The construct encoded SEQ ID NO, 19 fused to a human Kappa light chain constant region.
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