Examples of 'human variable' in a sentence
Meaning of "human variable"
human variable: In psychology and social sciences, human variable refers to an aspect of behavior or characteristic that can vary among individuals, affecting an experiment or study
How to use "human variable" in a sentence
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human variable
The human variable region to be used to elicit antibodies.
There is still the human variable.
Selection of the human variable regions is considered to be of critical importance.
Methods of making a nucleic acid encoding a human variable region.
The most homologous human variable region sequence was determined for each antibody.
Exemplary libraries for screening are human variable gene libraries.
The human variable light chain region was cloned into an LgK expression vector.
This project will concentrate on the human variable in the development process.
The human variable domain which is most homologous is chosen as the framework for humanisation.
Mice expressing an immunoglobulin hybrid light chain with a human variable region.
Producing hybrid antibodies containing human variable regions and rodent constant regions.
In a particular embodiment, the antibody of the invention is or comprises a consensus human variable domain.
A method of producing an antibody comprising a human variable region and a rodent constant region.
In one aspect, the immortalized cell line expresses an antibody that comprises a human variable domain.
The TCR may therefore comprise human variable regions and murine constant regions.
See also
For example, the FRs of the sdAbs can be replaced by human variable FRs.
In cases where human variable domains are preferred, chimeric scFvs can be used.
Rodent capable of producing hybrid antibodies containing human variable regions and rodent constant regions.
Table 11 shows human variable region usage in hybridomas from transgenic mice.
The heavy chain variable region can be a humanized or human variable heavy chain variable region.
The first series human variable region cDNA 's were synthesized by Operon.
The term " human antibody " relates to an antibody containing human variable and constant domain sequences.
Common human variable factors include susceptibility, flight hours, fitness, and medication / drugs.
In certain embodiments, at least one residue in the human variable framework region is substituted.
A number of human variable light ( VL ) and variable heavy ( VH ) consensus sequences have been identified.
Subsequently, the thus humanized, reconstructed human variable region is ligated to a human constant region.
Nevertheless, the murine part contains sequences 80 % homologous with the human variable regions.
A method for selecting a human variable region for making a bispecific antibody, comprising,.
Well, there's a win for the human variable.
Then, the humanized reshaped human variable region is ligated to the human constant region.
Initially, high affinity chimeric antibodies are isolated having a human variable region and a mouse constant region.
IGHV1-69 human variable heavy chain germline acceptor amino acid sequence.
In another specific aspect, the human variable domains are Vλ domains.
Resultant antibodies possessed human variable regions and human IgG1 and lambda constant regions.
In this case, the human variable.
In a specific aspect, the human variable domain comprises rearranged Vk and Jk gene segments.
In another specific embodiment, the human variable domains are Vλ domains.
In a specific aspect, the human variable domains are human Vk domains.
In a specific embodiment, the human variable domains are human Vk domains.
In one embodiment the single human variable segment is a VH1-2 segment.
In one case, the single human variable segment is a VH1-2 segment.
AAZ0906 shows the acceptor human variable light chain sequence.
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