Examples of 'ifns' in a sentence
Meaning of "ifns"
IFNs stands for Interferons, which are a group of signaling proteins made and released by host cells in response to the presence of several pathogens
How to use "ifns" in a sentence
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ifns
The goal of my thesis was to identify regulatory mechanisms of IFNs signaling.
The mechanisms by which IFNs exert their effects are not completely understood.
It can be expected that a similar approach would be effective for IFNs produced by pDC.
The injection of IFNs in the muscle or under the skin is generally well tolerated.
PDC is a cell that produces most of IFNs in a living body.
IFNs belong to the large class of glycoproteins known as cytokines.
Several jurisdictions across Canada have different ways of calculating IFNs.
IFNs are glycoproteins produced by immune cells in response to viral infection.
The IFN receptor also determines the high degree of species specificity characteristic of the IFNs.
Type I IFNs are preferable IFNs in the present invention.
OAS is expressed at low constitutive levels and is induced by type I IFNs.
Type I IFNs enhance the terminal differentiation of dendritic cells.
New modes of action and biochemical pathways regulated by Type I IFNs are continually being discovered.
Type I IFNs are critical for antiviral immunity.
Some STATs are activated by both type I and type II IFNs.
See also
Functional lizard type I IFNs can be found in lizard genome databases.
There is often an attempt to express these requirements as instream-flow needs IFNs.
Where indicated various IFNs were added at day 0.
In addition, the IFNs have been used in combined form exploiting their synergistic effects.
The IFN antiviral activity is partly due to IFNs induced enzymatic systems, such as,.
IFNs are part of the non-specific immune system.
When used in systemic therapy, IFNs are mostly administered by an intramuscular injection.
Figure 7 is a comparison of amino acid sequences between type I human IFNs.
While the antiviral effects of IFNs are well characterized, their immunomodulatory properties are less clear.
Antiviral and antiproliferative effects specific to type I IFNs result from p38 MAP kinase signaling.
In some contexts, IFNs increased the radiation sensitivity of NK cells.
PKR is constitutively expressed, and induced by type I IFNs.
In addition, class I IFNs may protect the fetus from immunologic rejection and viral infections.
Currently, IFN-Y and one subclass of IFN-a are the only type II IFNs.
Conversely, type I IFNs are also prescribed as therapeutics in other disease indications.
Specific binding was determined as described above for 125I-labeled IFNs.
The IFNs exhibit anti-viral, immunoregulatory, and antiproliferative activities.
The preparation of recombinant IFNs is known, for example, from Gray et al.
IFNs demonstrated no dose- or schedule-dependent effects.
There is an overall homology of about 20 % between IFN-B ₂ and the other type I IFNs.
Increasing amounts of IFNs further decreased tumor cell proliferation ( Figure 4 ).
These IFNs signal through a receptor complex consisting of IL10R2 and IFNLR1.
Recent studies indicate that type I IFNs might also influence DC differentiation and maturation 15 ; 16.
IFNs have antiviral, anti-proliferative and immunoregulatory functions Baron, S. et al.
The effect of type I IFNs on IL-3Ra expression has never been assessed before.
Type I IFNs further activate p38 mitogen-activated protein kinase ( MAP kinase ) to induce gene transcription.
Turtle type I IFNs have been purified references from 1970s needed.
Type i ifns ( ifn-α / β ) are important for host defense against viral infections.
The three major IFNs are referred to as IFN-a, IFN-B and IFN-Y.
