Examples of 'immortalized cell' in a sentence
Meaning of "immortalized cell"
Immortalized cell: A cell that has been altered to prevent its natural process of aging and cell death, allowing it to continuously replicate in laboratory conditions for research purposes
How to use "immortalized cell" in a sentence
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immortalized cell
Cell transduction assay of immortalized cell lines.
The immortalized cell may be a hybridoma.
The cell may also be an immortalized cell.
More specific immortalized cell lines are murine myeloma lines.
The disclosure descreibes that a eukaryotic cell is an immortalized cell.
Such immortalized cell lines may be produced in a variety of ways.
The resulting hybridoma is an immortalized cell that produces antibodies.
Additional methods are provided for the disimmortalization of an immortalized cell.
Immortalized cell lines are preferred in the methods of the present invention.
Usually the mammalian cell hosts will be immortalized cell lines.
A hybridoma is an immortalized cell line producing the antigen binding protein.
Disclosed is the use of a mouse as described herein to make an immortalized cell line.
Methods to obtain immortalized cell lines of types of mononucleocytes are known in the art.
Such cells may comprise a primary cell culture or an immortalized cell line.
An immortalized cell producing the desired antibody may be selected by a conventional procedure.
See also
Conditional immortalization provides immortalized cell lines with stable metabolic functions.
The adipose tissue may comprise a primary cell culture or an immortalized cell line.
The invention further provides immortalized cell lines producing such antibodies.
Suitable mammalian cells include primary cells and immortalized cell lines.
A hybridoma is an immortalized cell line which is capable of secreting a specific monoclonal antibody.
The cells may be primary cell cultures or may be immortalized cell lines.
The myeloma cell lines are immortalized cell lines that do not produce antibodies.
An additional aspect of the invention provides methods for the disimmortalization of an immortalized cell.
In another aspect of the disclosure the immortalized cell line is a human cell line.
The immortalized cell lines can be stored in various gene banks around the world.
Other methods involve isolation of rearranged Ig gene sequences and cloning into immortalized cell lines.
The invention also provides immortalized cell lines that produce an antibody of the invention.
In one embodiment, the cell is an immortalized cell.
A hybridoma or immortalized cell line is also provided that secretes a monoclonal antibody of the invention.
In another embodiment, a eukaryotic cell is an immortalized cell.
The production of immortalized cell lines derived from human skin tissues has been previously described.
For example, a mammalian cell can be an immortalized cell.
The immortalized cell or progeny thereof may be of B lymphocyte origin.
In a more preferred embodiment, the immortalized cell is a hybridoma.
An immortalized cell line secreting an antibody of claim 1.
In other cases, the mammalian cell is an immortalized cell line.
Optionally, the immortalized cell line is a rabbit hybridoma or a mouse hybridoma.
In one embodiment, the invention provides conditionally immortalized cell lines.
Immortalized cell line capable of producing monoclonal antibodies according to claim 7.
In another embodiment, the cells are immortalized cell lines derived from a subject.
An immortalized cell producing a monoclonal antibody according to any one of claim 1 to 9.
In one preferred embodiment, the immortalized cell line is a rabbit or mouse hybridoma.
An immortalized cell line made from the isolated rodent cell of claim 7.
This phenomenon is observed in immortalized cell lines, in primary cells and in stem cells.
Such cells include cultured cells as well as primary, secondary and immortalized cell lines.
Generating immortalized cell lines from said single cell suspension ;.
Depending on the vector system, many different immortalized cell lines may serve as suitable hosts.
Immortalized cell lines from human adipose tissue, process for preparing same and applications thereof.
In one preferred embodiment, the immortalized cell line is a rabbit hybridoma or a mouse hybridoma.
Immortalized cell line capable of producing monoclonal antibodies according to any of claims 4-7.
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